Dr. Romesberg dismissed concern that novel organisms would run amok and cause harm, saying the technique was safe because the synthetic nucleotides were fed to the bacteria. Should the bacteria escape into the environment or enter someone’s body, they would not be able to obtain the needed synthetic material and would either die or revert to using only natural DNA.
Yeah, and we all know how well that worked out with the dinosaurs in Jurassic Park.
This seems like a poll from yesterdecade. I use all of OS X, Linux and Windows on a regular basis - often on the same computer at the same time. What is the task you are trying to accomplish? What is/are the best available tools to accomplish that task? Use them.
You will lose an important tape file.