oh man...so is crazy genetic?
no...but this study is from the University of Washington St. Louis wants to say it is...they analyzed data and this is what they conclude, from full text:
Schizophrenia is a group of heritable disorders caused by a moderate number of separate genotypic networks associated with several distinct clinical syndromes
That's what they say..."group of heritable disorders"...it reminds me of when I studied Mendell in HS science and fruit flies and hemophilia.
It sounds fish as hell to me...psychology is great but it's so often wrong. ex: one year the DSM lists 'homosexuality' as an actual disorder...next year...not a disorder! magic!
again...i actually love psychology...but it's just full of random theories from the 19th century that are floating around...so many disorders to describe very similar and overlapping symptoms...symptoms very often open to interpretation...
I wanted to see if this passed the basic "correlation is causation" test...because this is just spreadsheets here these guys are looking at...they are re-analyzing data.
From the full text:
The 4,196 cases and 3,827 controls in the MGS study were combined to identify SNP sets. We had data of good quality on 696,788 SNPs on these cases and controls, and **from these we preselected 2,891 SNPs that had at least a loose association (p values,1.031022) with a global phenotype of schizophrenia (see the data supplement)**.
Emphasis added. Honestly that's enough for me to want to see it for myself, the actual data on a computer screen, before I give this any credence.
Obviously mental disorders exist. Just like anything it is related to our genetics and our environment and our choices...I would need to see alot of evidence before I believe TFA's assertions to the heritability.
Examine this list of behavior (copied from wikipedia which quotes the DSM):
According to the revised fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), to be diagnosed with schizophrenia, three diagnostic criteria must be met:
Characteristic symptoms: Two or more of the following, each present for much of the time during a one-month period (or less, if symptoms remitted with treatment).
- Disorganized speech, which is a manifestation of formal thought disorder
- Grossly disorganized behavior (e.g. dressing inappropriately, crying frequently) or catatonic behavior
- Negative symptoms: Blunted affect (lack or decline in emotional response), alogia (lack or decline in speech), or avolition (lack or decline in motivation)
If the delusions are judged to be bizarre, or hallucinations consist of hearing one voice participating in a running commentary of the patient's actions or of hearing two or more voices conversing with each other, only that symptom is required above. The speech disorganization criterion is only met if it is severe enough to substantially impair communication.
- Social or occupational dysfunction: For a significant portion of the time since the onset of the disturbance, one or more major areas of functioning such as work, interpersonal relations, or self-care, are markedly below the level achieved prior to the onset.
- Significant duration: Continuous signs of the disturbance persist for at least six months. This six-month period must include at least one month of symptoms (or less, if symptoms remitted with treatment).
I want to say that if you talk to a "good" psychiatrist or psychologist they will be able to explain how *they* personally in practice diagnose these different disorders and it may make sense. Furthermore, I'm convince psychology is a great area for scientific investigation.
All that said, as I look at that list of behaviors, then I look at the data as presented, I can only conclude that "schizophrenia" is *probably* an obsolete distinction and this data is being erroneously interpreted.