Alcohol? Great as long as you don't drive, don't urinate in public or start a drunken brawl.
Drugs? Great as long as you don't end up sitting in the ER on public dollars, or don't go on a lunatic stabbing rampage.
Smoke is probably the worst of the lot in terms of the number of people it affects. It smells foul (opinion) and it's bad for your health just being in the same room or general vicinity as someone who's doing it (fact).
Did you type that with a straight face? The sociological and economic impact from alcohol and drug abuse is so massive and ubiquitous it's pretty much impossible to be quantified.
What you are saying is: "I'm ok with these things when I remove the horrific aspects of them, but not with smoking."
There's like a million arrests per year for DUI (just the people who get caught), but let's focus on that terrible smoker doing things that you don't like.