One of the primary uses for my laptop is as an audio workstation. If I'm at home I connect an external keyboard and mouse directly to 2 of the ports. The third port connects to a powered hub that connects a 61-key synth, a 25-key midi controller, a contoller pad, an external track controller, an audio interface, and a secondary audio interface that allows me to use tablets and smartphones as additional controllers/input devices. And a large external backup drive that I don't leave connected all the time.
Grand total of 10 devices if you include the usb hub itself as a device. 12 devices if you include a tablet and phone connected to the special interface.
On the road I'll just plug in a mouse and maybe the 25-key controller if I want to do any music work at the hotel as a break from the grind. My actual job is in security, the music is a very serious hobby.