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Submission + - Moffitt Cancer Center researchers investigate a potential new tumor suppressor (

ericjones12398 writes: "A tumor suppressor gene acts as a molecular guardian against cancer by protecting the cell from various forms of damage. "p53" is a tumor-supressing protein that functions as an anti-cancer gene in several ways. Early this week researchers reported the identification of a transcription factor that regulates p53, an important step towards better cancer treatments."

Submission + - Restructuring aneurysms (

ericjones12398 writes: "An estimated six million Americans harbor an aneurysm. Aneurysms occur when artery walls are weakened, causing a saclike bulge in the blood vessel. People can live symptom free with aneurysms, but if one grows big enough and ruptures, it will be fatal 40 percent of the time. Even if someone survives a ruptured aneurysm, the patient will most likely suffer permanent neurological damage and/or disabilities.
Current treatment protocols for aneurysms focus on preventing the rupture of the aneurysm via blocking blood flow to the bulge. The first treatment option was surgical clipping, which was introduced in 1937 by Walter Dandy. Surgical clipping required the opening of the brain and placing a clip at the base of the aneurysm. This clip prevents blood from entering the aneurysm. Although this procedure is quite invasive, the benefit is that there is a low reoccurrence rate with this technique.
The other popular option for aneurysm treatment is endovascular coiling. This less invasive procedure involves insertion of a catheter through the groin to place platinum coils at the aneurysm. These coils block blood flow into the area, thus, preventing rupture. While coiling is less invasive than surgical clipping, reoccurrence in the first year occurs in 28.6 percent of patients and increases over subsequent years."


Submission + - New diabetes treatment combines insulin and hormone therapy ( 1

ericjones12398 writes: "Since the introduction of therapeutic insulin in the 1920s, continuous efforts have been made to improve diabetes treatment. Some of the commercially available insulin formulations are characterized by a fast onset of action, while other formulations have a relatively slow onset but prolonged action. Because people suffering from diabetes are subject to chronic treatment over several decades, there is a major need for safe, convenient and life-quality improving insulin formulations."

Submission + - Thick skinned no more: Transdermal delivery gets drugs under the skin (

ericjones12398 writes: "First transdermal patch was approved in 1979 and the number of new transdermal drugs is steadily rising, the type of drugs amenable to this route of administration remains limited. When thinking of transdermal patches, I think of nicotine and birth control patches. Why do these drugs work transdermally, but others do not? Well, certain compounds can pass through the skin without added help, but most can't. To avoid invading pathogens, our skin provides a first line barrier — it's outer most layer, the watertight stratum corneum. To get through the stratum corneum, a drug needs to diffuse through intercellular lipids along a path that winds through interlocking cells. This transport pathway limits the types of molecules that can pass though. Compounds that work well for unaided transdermal delivery must be lipophilic with low molecular weights. Additionally, these compounds need to be effective at low doses. As long as a drug fits these standards, transdermal delivery is feasible"

Submission + - Taxing junk food: A new public health campaign against obesity ( 2

ericjones12398 writes: "Today, many developed and developing countries including European Union nations, Australia, South Africa, Egypt, Turkey, Bangladesh and Vietnam apply excise taxes on unhealthy products. Research has shown that both for tobacco and alcohol, excise taxes are an effective way of reducing consumption. With respect to tobacco, a 10 percent price increase in cigarettes is shown to reduce demand by 4 percent in high-income countries and by 8 percent in low-middle income countries. Taxes imposed on cigarettes have not only prevented people from starting to smoke, but have also reduced rates of relapse for those who recently quit smoking."

Submission + - New medical apps are on the horizon, but will your doctor use them? (

ericjones12398 writes: "Experts say the medical industry drives innovation; perhaps it does, because the need for advanced medical care is constant in a changing world. We’ve talked about digitization of medical records and radio frequency identification (RFID) chips — two examples of a wireless, paperless health care industry. The world of mobile apps is also evolving quickly, and medical apps are no exception.
There are a wide range of medical apps available for mobile devices designed to help you and your doctor reference general information about medical conditions, access health records using voice recognition technology, and perform an eye exam. You’ll be amazed at how smart your smartphone can be, with these innovative health-care apps coming soon."


Submission + - Crowdsourcing and cloud computing: Putting the future of innovation in consumers (

ericjones12398 writes: "Innovation has been occurring thanks to the ongoing development of social media platforms — like Facebook — in tandem with websites that leverage crowdsourcing — like Kickstarter. In practical terms you have ordinary individuals across the globe, who understand what they want, assigning value to inventions by providing immediate feedback and financing. This is counter to the trend which was once prevalent in the technology sector where engineers and programmers create products and their companies in turn assign the value to those products."

Submission + - Collaborative research utilizes 'social networking' science to identify IQ gene (

ericjones12398 writes: "The research appears in the latest edition of the journal, Natural Genetics, and compiles 200 scientists’ data from 21,151 test subjects worldwide. Professor Thompson likened the collaboration to Wikipedia — an internet-based encyclopedia that no one person could write in a lifetime, but which exists because of widespread cooperative input. In Thompson’s words, the study is “crowd-sourcing brain research . . . [and] bringing social networking to science.” Thompson and his fellow researchers in Australia and the Netherlands had become frustrated with their inability to amass sufficient DNA scans from brain samples to pinpoint the targeted “IQ gene.” He recognized that the individual research centers couldn’t review sufficient numbers of brain scans to secure definitive results; but by collaborating through ENIGMA, they were able to create a sample large enough to reveal clear patterns in genetic variations linked to brain size."

Submission + - New Treatment for Depression and Anxiety may have fewer side effects (

ericjones12398 writes: "SSRIs have been on the receiving end of much criticism over the last several years, with opponents asserting that the treatment is ineffective and highlighting its suspected link to suicide in adolescents taking SSRI-based medications. Because depression and other central nervous system disorders are often diagnosed without performing any physical examinations, critics question the validity of claims that SSRIs function by correcting chemical imbalances. If the patients’ neurotransmitter levels are not constantly monitored, how can the treatment’s physical activity be evaluated? Without measuring the pre- and post-treatment neurotransmitter levels, physicians can’t be sure that they haven’t overcorrected any chemical imbalances, and this may lead to further psychological issues."

Submission + - SPAM: Incentives needed for health research affecting developing countries

ericjones12398 writes: The Consultative Expert Working Group on Research and Development: Financing and Coordination (CEWG) of the World Health Organization (WHO) called for increased global commitment to funding and coordinating health research to meet the specific needs of developing countries.
Link to Original Source

Submission + - Record broken for energy-conversion with new tandem polymer solar cells at UCLA (

ericjones12398 writes: Researchers at UCLA’s school of engineering and UCLA’s California Nanosystems Institute (CNSI) have developed a device to convert sunlight into electricity efficiently and cost effectively using organic polymers. UCLA’s Yang Yang’s research team has built a device with a new 'tandem' structure for power-conversion. In July 2011,

Submission + - German researchers conclude that ADHD is over-diagnosed, especially in males | P (

ericjones12398 writes: Researchers at Ruhr-University Bochum in Germany have concluded that attention deficit hyperactivity disorder (ADHD) is over-diagnosed based on the results of a new study. They surveyed a total of 1,000 child and adolescent psychotherapists and psychiatrists across Germany, with 473 ultimately participating.

Submission + - Does higher health care spending lead to better patient outcomes? (

ericjones12398 writes: If you haven’t seen the words “health care” in news headlines lately, you must be living under a rock. Health care reform, health care spending, Medicare spending, Obamacare; the list goes on and on. What I find most controversial among the latest research and news is an obviously flawed payment scale that undervalues primary care and overvalues specialty care. There is evidence suggesting that publicly funded health care spending (i.e., Medicare) has not based on primary health care needs. Rather, Medicare spending relies on a resource-based relative value scale (RBRVS) which promotes higher spending without evidence of better patient outcomes.

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