I have a friend with Friedrich's Ataxia, and CRISPR is one of the silver bullets she's praying for. FA cripples then kills you: wheel chair by 25, dead by 40 is often the case (it hardens the heart so it can't pump). While CRISPR has some unknowns and risks, having FA is a certainty. FA affects a single gene pair, so if you can replace either side of that gene, you have solved the problem, the mitochondria will start producing frataxin again, and the nerves will stop being slowly destroyed.
There are no treatments and since it is so rare (1 in 50,000 have it in the US, 1 in 30k in Europe, almost no one in Africa or Asia), few are investing in finding a cure or treatment. FA isn't the only orphan disorder like this. So yes, I'm quite happy to see CRISPR move forward.