While I agree whole-heartedly with open science/open access, most public research in California is federally funded, not state funded. Although some institutes, like the NIH, require publication to journals, the journals themselves can and do have commercial policies. This is where real battle is currently being waged.
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Bioinformatics has been very happily open source and Linux friendly for my entire career to date (14 years). Only the last two and a half of those 14 years have been whithin acedamia, but open source is an especially easy sell here.
As anyone supporting nextgen sequencing will know, researchers will claim that they simply must have the raw data. My dissuading answer: OK, then THIS is how much it is going to cost you. Payment due in full before data acquisition.
10 yeast cells clumped together have more mass than 1 yeast cell. Therefore they sink to the bottom of a tube.
Bzzt. Please review the difference between mass and density and the relationship between density and buoyancy.
I agree completely.
One great advantage in using insect cell lines is that they do not require serum to grow, which is both costly and open to the risk of transmitting zoonotic pathogens. Insect cells can also be more robust than mammalian cells in large scale fermentation conditions.
Whistler: Anybody want to crash a couple of passenger jets?
I designed a parallel PCR detection system for that is definitive, more sensitive, faster, and a hell of a lot cheaper. I'll bet a lot of other people have, too. If higher resolution is needed, then you could simply couple it with a pyrosequencer. There are many ways to skin this cat.
I had a boring job at a contract lab in Switzerland. It was the middle of winter in 1998. I installed slackware on a laptop and learned C and Perl. I moved back to California to another boring job, but kept up. After two years and a lot of work, I became the head of bioinformatics at a startup biotech company. I taught Perl and bioinformatics courses at the local universities, but have stayed in industry ever since. I picked up a lot of skills along the way, from building HPC pipelines on clusters, RDBMS (postgres), serving up information through LAMP, and building novel pattern recognition and visualization systems.
Linux is now second nature and my whole family uses it for computing and on various devices around the house. I can't imagine going without it
I recently built out an all analog stereo (turntable, tube amp, and delicious folded horn speakers) to justify inheriting my fathers LP collection, which is mostly jazz and classical. I typically hunt for new music to add to the collection by reading on line reviews, listening to samples, downloading albums by the same musicians that I find on Pirate Bay, and then depending on what I hear, deciding to commit to purchasing on vinyl. I buy about one LP album per week and that is mostly due to Pirate Bay.
AND he used ssh for remote logins. Burn him!
What?! Are the anti-academics claiming that the university curriculum is liberal or fascist? You can't possibly be claiming both, because that would be ignorant. Oh, right. Never mind.
...it just smells funny.
My "old" analog medium and large format cameras and lenses cost far less and offer better resolution. You'll have to pry them from by cold, silver-stained fingers you digital whipper-snappers!
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