Helium is "manufactured" by radioactive decay underground. Also, He is unnecessary for life. You only need it if you want a funny voice, or poor lift from something less flammable than H. Aside from some uses as a coolant, we wouldn't lose much if there was no He left.
Helium has a lot more uses that you seem to understand. Particularly as a superconductor (not a coolant). Without it there would be no high field MRI scanners. As far as I know, there are not permanent magnet MRI scanners above