My ethical problem would be that in the short-medium term, we don't understand what we're doing and will hurt more than we heal.
So need a few more decades with animal testing.
After that? Open the floodgates. Not everyone will want the 6'2" white blonde blueeyed children. I can see a market for catpeople, dogpeople, merpeople (colonise the oceans!); I'm sure there'll be one or two who want to incarnate Cthulu; wings capable of unaided flight might be difficult.
Never worry about being the wrong skin colour as everyone will be any colour of the rainbow - or even rainbow coloured!
Nightvision - eyeshine a reality!
Solar powered - get a lot of your daily calories just by standing naked in the sun.
Turn hair-growth on and off. Never have to shave again.
People who worry about eugenics are just lacking in imagination.