I don't know about that. Does anybody do pay-per-view ads anymore? I was under the impression it was mostly pay-per-click. Honestly, I can't remember the last time I clicked an ad, and if I did it was entirely an accident. Unless you're going to go so far as to argue that readers are obligated to click ads on sites they surf to generate money for the site, there isn't a whole lot of functional difference between browsing with ads blocked and ads visible for users who don't click.
Functional difference for the site, that is. From the user perspective there's potentially a big difference, in terms of bandwidth, clutter, and possibly security.