The fruit of knowledge. There was a reason the bible described things as it did. Knowledge isn't just the anti-christ, it's the anti-god.
If your 'knowledge' of the Bible only extends as far as an ignorant half-remembered version of Genesis, then yes.
Specifically, it's not "the fruit of Knowledge" - it's "the Knowledge of good and evil".
The Bible is actually quite encouraging of knowledge, even showing something of a kickarse attitude towards deliberate ignorance:
"An unfriendly person pursues selfish ends and against all sound judgment starts quarrels. Fools find no pleasure in understanding but delight in airing their own opinions ... The lips of fools bring them strife, and their mouths invite a beating ... Before a downfall the heart is haughty, but humility comes before honor. To answer before listening - that is folly and shame ... The heart of the discerning acquires knowledge, for the ears of the wise seek it out."
-- Proverbs 18:1-2,6,12-13,15