Certainly; cost is always a factor, including for nuclear. Almost anything is possible, given enough time & money, but cost effectiveness is still paramount - IF you consider all significant lifetime factors, including capital, ongoing, post-lifetime, and at least best estimates of external societal costs.
I'd love to see more comprehensive levelised cost comparisons of a much wider range of grid options, including solar & wind backed by a range of different storage technologies, nuclear, and even fossil-fueled options too. It'd be fascinating to see how these have been changing over time, and how they change by site, payoff times, residual/decomissioning costs and externalities. Too much discussion is reduced to "it just isn't practical" and "this is better, because reasons", or "that would be too expensive".
This AETA updated report on energy options for NSW, Australia, is an excellent start, and has some great information in graph form towards the end, including . Unfortunately, a change in government since the original report has resulted in carbon prices being excluded, which is unfortunate as that was a reasonable proxy for the many external costs to society, but even without that it can still add some much needed reality to the picture. Got any links to even more comprehensive studies?