Adobe Lightroom - does 95% of what I would do with photoshop, works on raw images and simplifies my workflow tremendously. I almost never use photoshop anymore.
Ubuntu, Windows 8.1, Libreoffice, Adobe Reader, - self explanatory.
Firefox with Adblock plus and Better Privacy and HTPS Everywhere installed.
KeepassX - Password manager. Multiplatform, much less buggy than Keepass2 (note to develepers: please take it out of alpha status!)
F.Lux - warms up the color of your monitor in the evenings so that it doesn't interfere with your circadian rhythm, hopefully improves sleep. (hey - it's free!)
Videolan (VLC) - excellent video player (despite the crappy name)
Sandboxie (paid $$) - Sandbox your browser and various other programs
FastOne Image Viewer - excellent, free sildeshow software
Secunia PSI - makes sure your programs are kept up-to-date