Since there is little friction in space what is there from stopping us from reaching an appreciable fraction of the speed of light? I was reading that we might attain lightspeed in about 1 year at 1G acceleration rate which only adds a couple of years to the trip..
Using force = mass * acceleration, energy = force * distance, distance = 1/2 * acceleration * time^2, and e=mc^2:
to accelerate a 1000kg payload at 1g (9.8m/s^2) for 1 year:
Energy to do so: 4.8 x 10^19 J
Equivalent mass of that energy: 532kg. That's also assuming Newtonian physics (no relativity), and not counting the fact that you have to account for the mass of the fuel. Let me know when we can produce 216kg of antimatter and then "burn" it in a controlled manner that directly corresponds to thrust.
If you use an energy density of 50,000 Wh/kg (very aggressive estimate of high-end energy density in current/near-future rocket tech), you're talking about needing over 2 billion metric tons of fuel (and don't forget you have to accelerate all that fuel too which now means you're no longer talking about a 1000kg payload.