Think of it this way... design a blueprint of your building in something like sketchup, and tag all the different surfaces according to type. Then put antennas in strategic places in the structure (could do 3 in each room, or surround the entire building) and turn on the multiband antennas.
The RF interference should be able to be mapped in this way fairly easily; especially if you set state and then open/close doors, turn WiFi on/off, turn on lights/heaters, etc.
Record all this state information, and then with minimal training, the system should be able to identify all mobile objects and when they moved.
If you toss in the RFID chips here, you could serialize each major mobile item, and actively track them anywhere in the structure.
This isn't new, and doesn't need all that much knowledge of RF, just a good AI that can learn.
See: http://www.extremetech.com/ext... for one way it's been done.