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Comment Re:Germline ethics (Score 1) 385

Gene editing is the future of medicine, as well as stem cells. The sad truth is that these technologies are working. Stem cells and Gene editing tools like CRISPR are indeed working. The problem is that we are like a 15 year old with all the tools to fix a car. Without experience, we don't know how to approach something as simple as replacing brakes, let alone rebuilding a engine.

I'm more worried about how we'll adapt this medicine over traditional medication. Lets say you have diabetes and need insulin shots to survive. You have to take these shots everyday for the rest of your life. OR, we could use gene editing to correct the gene so that you produce your own insulin. It would be a single shot and you're done. This could be a huge blow to pharmaceutical companies and they'll likely encourage people to be against these kind of therapies.

Sad truth is that gene therapy is the future of medicine and we could delay that future for whatever morality we're trying to hold onto, or we could embrace it and save lives now. If that means we won't be old any more and populations would increase, then those are problems I'm willing to deal with. Condoms and safe sex can easily solve that problem, and people won't die. Good chance the longer you live the more likely you'll do something stupid like put a fire cracker in a gas can.

Comment Re:As a geneticist, Church knows zero about ageing (Score 1) 385

Everything that goes on in your body is genetics, especially ageing. Why do some animals live nearly forever like molerats? It isn't their diet that's for sure. In fact SENS is working on moving Mitochondrial DNA into the nucleus cause the nucleus is very good at repairing DNA damage and protecting it compared to the Mitochondria. According to SENS, this is something nature was already in the middle of doing and they're just trying to complete the task.

So yes, Metochondrial DNA damage does cause ageing. Therefore DNA is very important part of ageing. Besides the fact that everything in the human body is in one way or another controlled by DNA, including ageing.

https://www.youtube.com/watch?...

Comment Re:Drawbacks (Score 1) 385

Money won't be a thing in 70 years. At some point automation will take away enough jobs that some serious changes will need to happen to accommodate this. One that'll likely happen soon is working less hours which is something that's been in the talks lately. Eventually you'll see money go extinct and all we'll do is trade, and most trading will happen between countries.

Comment Google Liz Parrish (Score 2) 385

Not many people know that Liz Parrish is patient zero for her company BioViva. They used gene therapy to try and reverse ageing in her to see if it works. They used two genes, I forget what they're called but the idea was extend the telomeres. Every few months they'll be testing to see how she's doing and if any ageing was indeed reversed.

Keep in mind that BioViva used viruses and not CRISPR to do this. Even if this doesn't work, it's just a matter of time before they find the right genes needed to reverse ageing. That's what the Google backed Calico is all about. It's very feasible that within 5 years we'll find the right combination of genes to reverse ageing. Doesn't mean that within 5-6 years you'll visit your doctor and get CRISPR injections just yet. Clinical trials will take 10 years before all this is approved, at least.

Comment Need better batteries (Score 1) 399

Bill Nye keeps repeating this and I think he's right. If we load homes with solar panels and use a giant plant that uses a heavy piston to take extra solar power and store it as fluid that pumps into the cylinder. Then at night it drains out the fluid to turn a turbine and produces power to local homes. Fusion is just another expensive power plant.

https://www.youtube.com/watch?...

Comment Re:It's all about aging, stupid. (Score 1) 204

There's many people but these are the ones that come to mind. They obviously do age but do so very well it looks as though they have stopped. They believe it's due to enzymes that you get from eating food raw. Rubbish. Your stomach breaks down the enzymes so something else is going on. My belief is that because they're so focused on what they eat and take care of themselves they have less oxidation stress. They obviously get a lot more vitamins. The best explanation I have is that they avoid a lot of carcinogens. No cooked food means nothing burns and generates free radicals. Just being a vegan isn't enough cause if you eat French fries you're on the vegan diet but it's obviously very bad for you.

This 70 year old who looks 30.
https://www.youtube.com/watch?...

This 44 year old looks 20.
https://www.youtube.com/watch?...

Generally all these people.
http://consciousnourishment.or...

Comment It's all about aging, stupid. (Score 1) 204

The way we do medicine today isn't very different than what we did 100 years ago. We find a chemical that does things, test said chemical and prey the side effect doesn't kill the patient. Surgery and our understanding of the human body is 1000x better than what we did 100 years ago but what we do is surface level treatment. You get sick and we find a way to fix said sickness. Heart has clog? Thin the blood like crazy with medicine. Stents to expand veins to keep them open and working. But that's like your engine leaks oil but instead of fixing the core of the problem lets put in thicker oil to slow the leak.

About 2/3 of deaths to people are age related. Heart disease, cancer, Diabetes, and etc are all age related diseases. And yes you can get them young but the moment you're born you're aging. What is aging? Aging is the process of the human body slowly building up damage, and there's 7 of them. People won't live past 80 or 90 if we don't fix aging first, and a lot of other diseases like Alzheimer is dependent on our ability to cure it. Cancer itself is caused by aging cells. We know the core cause of cancer is telomeres which protect the cell from damage. Most cells in your body don't extend these but cancer cells do and indefinitely and become immortal.

There's already discoveries found that help with aging and health significantly. For example back in 2003 they found a chemical called Resveratrol. This stuff is so amazing that it doubles the life of mice, which don't live for very long. They're younger and healthier for a longer time, and don't develop sicknesses easily like diabetes, especially on a western diet which is very bad for you. Resveratrol doesn't stop or reverse aging but it does significantly slow it down and you can buy it right now off online stores. It's proven to work, but everyone is trying to make a more concentrated and potent version of Resveratrol. There's compounds which are proven to extend telomeres which many people consider the holy grail of age reversal for humans and our best defense against cancer. The compounds are unfortunately only 5% effective so people who took the compounds didn't look or feel younger but their cells did look younger. Now they're trying to find compounds that are more potent and they have, but they'll kill you.

My point is that if we're to make people live healthier and better lives than we need to look into aging itself, and my prediction is that within 15 years we'll have methods to drastically slow aging. About 20-25 years from now we'll be able to stop aging but not reverse it. Within 30-40 years we can actually reverse aging mostly. I say mostly cause you may look 20-30 years old and feel 20-30 years old but you'll still have some age related issues to deal with. I'm not sure when and if we'll be able to fix Mitochondrial mutations or even DNA mutations, but it might not be a real issue. Human body is really good at repairing DNA. For now I would avoid high sugar foods, and cooked foods that have lots of carcinogens. Resveratrol works and is on sale as a vitamin. People on raw vegan diets don't age. Though that means eating uncooked food and no meat which many people probably won't do.

It's also a big problem that we don't look at aging as a disease when it causes so many and effects people of all ages, it just effects older people more so than younger.

http://www.sens.org/research/i...
https://www.youtube.com/watch?...
https://www.youtube.com/watch?...

Comment Re:Quothe the raven, "Forevermore". (Score 1) 205

I believe that big bangs occur multiple times throughout the universes history. A giant hyper massive black hole gets big enough that it explodes like the big bang. There might be other hyper massive black holes that are pulling on galaxy's far away and might explain dark energy. Black holes are the universes recycling centers. Life may have existed far before 13.5 billion years ago and the universe maybe infinite.

Course that's just and idea I came up with.

Comment There's no money in the future (Score 1) 615

Like in Star Trek, the future will be without money. Three things that will be the downfall of money. One being all jobs will be replaced with autonomous systems. You don't need a person to drive a truck or do your taxes or repair roads. Secondly is the cure for aging. It'll happen, and much sooner than you think. Imagine a person who looks 20 but is 100. Do we let those people stay retired or force them to work? Finally you have the future of abundance. At some point energy and food will be plentiful to the point there's no reason to work. The machines are doing all the work and they run off renewable energy.

Definitely will be the biggest and last class war the world will ever see in the future. I don't about flying around in space ships but we'll definitely be like a Star Trek economy in the future. Don't know about a food synthesizer though.

Comment Been there done that. (Score 1) 325

Honestly, I haven't found a good laptop that doesn't burn up. My experience HP, Compaq, Dell's have all had thermal issues. Worse yet, thermal issues that result in broken solder with the GPU or chipset or both. Have you ever turned on a laptop with nothing on the screen but blackness? Very common issue, even with Clevo based laptops. Resulting in me needing to use heat reflow with liquid flux.

I took every gaming cooling trick out of my bag, cause once you fixed the broken solder you have to prevent it from happening again. First I sanded the surface that touches the CPU and GPU flat as possible. Yes it's a lapping. Then I use black emery rouge compound with a dremel to get it smoother. Then some high quality non conductive thermal paste along with premium thermal pads like Fujipoly where needed. It makes a difference and non of my laptops go above 70C even under gaming.

The cooling in modern laptops aren't evolving as fast as the thermal output of these devices. Heat pipes aren't cutting it, and laptops should have started using water cooling. Yes, water cooling. Modern laptops use one or two heat pipes to cool the system where a simple water block would do a far better job. Desktop air coolers though use many heatpipes to keep the CPUs cool, while the GPU's enjoy wasting a PCI-E slot for its air cooler. With so many sealed water cooling desktop solutions, nobody bothered to make a laptop version?

Comment Give me back my Quad 4 (Score 1) 267

GM doesn't need to worry about Tesla. They have their own problems. All their cars look like Tonka toys and have the build quality of a Chinese iPhone knock off. They all use Vauxhall/Opel engines which are those stupid Ecotec engines. On the other hand their Corvette/Camaro's are awesome and with v8's can get nearly 30 MPG. Why hasn't any of that tech came down to their 4's which they decided to stick into nearly every car?

Can we just get back those Quad 4 engines? Why does a modern Ecotoc need 2.5L to produce the same power of a 2.3L Quad 4 W41 from 1990?

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