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Comment: Re:Know who to sue (Score 1) 158

by ColdWetDog (#47975393) Attached to: Anonymous Peer-review Comments May Spark Legal Battle

Can we all work in your fantasy world? At least in the biomed fields, even 'reputable' scientists are having hard times getting grants and tenure. Not saying that this guy is reputable at all but it's a paramecium-eat-ameoba world out there.

'Nature red in tooth' and claw and all of that

Comment: Re:Study subject not depressive (Score 2) 135

by ColdWetDog (#47961837) Attached to: New MRI Studies Show SSRIs Bring Rapid Changes to Brain Function

It's obviously the beginning of a research project. Take a drug - see what it does to 'normal' people with the testing platform you are using (in this case functional MRI), then try it on different clinical diagnoses. Remember, most medical diagnoses and especially psychiatric ones are not binary events - they lie on a continuum. We really don't know how to diagnose most patients with complex psychiatric problems. We typically give them several overlapping diagnoses that really don't explain the patient's problems and medicate them accordingly. I've always thought there should be a 'just plain nuts' category. It would be more objective and honest.

Treatment of psychiatric issues with medications is still in it's infancy and it's still akin to using hand grenades instead of scalpels. Studies like this one are trying to pin point areas of regulation and dysregulation with the eventual idea of finding more specific treatments.

Of course, that means more specific ways of controlling someone's mind. Which has its upsides. And it downsides.

Comment: Re:Interesting (Score 3, Interesting) 135

by ColdWetDog (#47961787) Attached to: New MRI Studies Show SSRIs Bring Rapid Changes to Brain Function

Although people are generally told that SSRIs take several weeks to work, many patients report that some effects are noticeable in the first few days. These are usually improvement in anxiety symptoms (depression and anxiety commonly coexist).

So this doesn't surprise me all that much. What will be interesting is to follow 'normal' and depressed people over time with and without treatment. However, given how annoying MRIs can be (confining and noisy and slow) I wonder if there will some sort of bias created with some people opting out of frequent testing.

Comment: Re: Most transparent ever? (Score 0) 252

by ColdWetDog (#47961023) Attached to: Mark Zuckerberg Throws Pal Joe Green Under the Tech Immigration Bus

Our rates went down from $1500/mo to $1300/mo for a family of 5 with medical, dental, vision, and prescription coverage. We're in Maryland and ages are 34, 34, 4, 3, and 3. We kept all of our doctors.

Oops. Missed one.

That's OK, we'll check on you next year as you re enroll. We've had some problems with our computer systems keeping up but we're working on it....

Comment: Re:Alright smart guy (Score 2) 495

by ColdWetDog (#47960663) Attached to: Ask Slashdot: Is iOS 8 a Pig?

That is why the prudent iOS User with hardware > 1 Generation "back", waits a few days/weeks to see if they should Upgrade. After all, all it takes to not Upgrade, is to, well, not Upgrade. You iOS Device will continue to work exactly as always.

The truly prudent iOS (or for that matter OS X) user waits until the .2 release to upgrade. That gives all of the beta testers, err, early users, time to debug the stuff that Apple, despite having a closed hardware platform, just never seems to manage very well. By the second point release, most of the mainstream bugs have been fixed as best they ever will.

Comment: Re:oh wow (Score 1) 128

by ColdWetDog (#47959717) Attached to: SpaceX Launches Supplies to ISS, Including Its First 3D Printer

I could even see circumstances in an Apollo-Thirteen kind of accident where engineers at NASA could come up with a fix that's safer and more reliable than duct-taping some plastic sheeting to a bulkhead because the tech to manufacture a few parts exists with those that need those parts.

As opposed to use socks and duct tape? Philistine. I weep for the world that was.

Uncertain fortune is thoroughly mastered by the equity of the calculation. - Blaise Pascal