Drives me nuts ever week or so asking me to install updates. It's a stupid pop-up updated app that gets triggered when a page with flash is loaded.
Yes I understand that running a browser non-stop for weeks goes against their updating philosophy. Too bad. The constant "Update now!" alerts just make their users more likely to fall for phishing scams.
Instead, if you can't update your plugin on already loaded pages... Refactor your app.
Make the bit loaded by the browser a wrapper that can allow its back end to update when convenient. Otherwise everyone who uses tabs is going to hate you. (Those who don't already)