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Science

+ - Drug Testing in Mice May Be A Waste of Time, Researchers Warn 1

Submitted by Anonymous Coward
An anonymous reader writes "A group of researchers including Dr. H. Shaw Warren of Mass. General Hospital and Stanford genomics researcher Ronald W. Davis have published a paper challenging the effectiveness of the "mouse model" as a basis for medical research, based on a decade-long study involving 39 doctors and scientists across the country. In clincal studies of sepsis (a severe inflammatatory disorder caused by the immune system's abnormal response to a pathogen), trauma, and burns, the researchers found that certain drugs triggered completely different genetic responses in mice compared with humans. The Warren-Davis paper was rejected by both Science and Nature before its acceptance by the Proceedings of the National Academy of Science, perhaps suggesting the degree to which the "mouse model" has become entrenched within the medical research community. Ninety five percent of the laboratory animals used in research are mice or rats. Mice in particular are ideal subjects for research: they are cheap to obtain and house, easy to handle, and share at least 80 percent of their genes with humans (by some reckoning, closer to 99 percent). Over the past twenty five years, powerful methods of genetically engineering mice by "knocking out" individual genes have become widely adopted, so that use of mice for drug testing prior to human clinical trials has become standard procedure."
Piracy

+ - Indie Game Dev Delights Pirate Bay-> 1

Submitted by jones_supa
jones_supa (887896) writes "Over the weekend a torrent of the game Anodyne was uploaded to The Pirate Bay and to the delight of observers was greeted with a positive attitude from its creators. 'It’s neat that Anodyne’s here and I’m glad that means more people can play it, though of course we’d love it if you bought the game,' the author Sean Hogan commented. Adding to the fun, Hogan posted up some codes so people could download the game for free from Desura. In an interesting turn, the torrent has later disappeared. The Pirate Bay is well-known for not removing torrents to any content — maybe the uploader started to feel bad about his act later?"
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Apple

+ - Dick Tracy's Watch: The Tech Meme That Won't Die->

Submitted by
harrymcc
harrymcc writes "Rumor has it that Apple is working on a smartwatch. The New York Times' Nick Bilton, who broke the news, and many other tech journalists, have brought up Dick Tracy's famous two- way wrist communicator in their coverage of it. That's not surprising--Tracy's watch always comes up in discussions of wearable communications gadgetry. And it has since 1947, shortly after the comic-strip cop first got his wrist radio. Over at TIME, I took a look at this seemingly indestrictible cultural touchstone."
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DRM

+ - W3C declare DRM in scope for HTML, big business supports Web DRM - Schism looms-> 1

Submitted by FredAndrews
FredAndrews (2736433) writes "The W3C has ruled DRM in-scope for their HTML standard. A lot of big businesses have supported advancing the Encrypted Media Extension (EME), including Google, Microsoft, and Netfix. The BBC calls for a solution with legal sanstions. The EME could well be used to implement a DRM HTML engine. A DRM enabled web would break a long tradition of the web browser being the User's Agent, and would restrict user choice and control over their security and privacy. There are other applications that can serve the purpose of viewing DRM video content, and I appeal to people to not taint the web standards with DRM but to please use other applications when necessary."
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+ - Judge hints at jail time for porn troll Prenda Law->

Submitted by rudy_wayne
rudy_wayne (414635) writes "A federal judge in Los Angeles has suggested serious penalties for Brett Gibbs, an attorney at porn copyright trolling firm Prenda Law. Facing allegations of fraud and identity theft, Gibbs will be required to explain himself at a March 11 hearing. And if Judge Otis Wright isn't satisfied with his answers, he may face fines and even jail time.

The identity theft allegations emerged late last year, when a Minnesota man named Alan Cooper told a Minnesota court he suspected Prenda Law named him as the CEO of two litigious offshore holding companies without his permission. Worried about exposing himself to potential liability for the firms' misconduct, Cooper asked the court to investigate the situation. Cooper's letter was spotted by Morgan Pietz, an attorney who represents "John Doe" defendants in California. He notified Judge Wright of the allegations."

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+ - Emergency Alert System hacked, warns dead rising from graves->

Submitted by
Rawlsian
Rawlsian writes "Great Falls, Montana, television station KRTC issued a denial of an Emergency Alert System report that 'dead bodies are rising from their graves.' The denial surmises that 'someone apparently hacked into the Emergency Alert System...This message did not originate from KRTV, and there is no emergency.'"
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+ - CNN Anchor wonders if asteroid is result of global warming.-> 1

Submitted by JDAustin
JDAustin (468180) writes "Proving that idiot anchors are not just on Fox News, a CNN anchor posed the question: "Talk about something else that’s falling from the sky and that is an asteroid. What’s coming our way? Is this an effect of, perhaps, global warming or is this just some meteoric occasion?”"
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Privacy

+ - Where is the safest place to host a website? 2

Submitted by aztracker1
aztracker1 (702135) writes "Given the number of intrusions in terms of U.S. (and its' allies) based hosting providers turning over data without a warrant, and rulings that consider "cloud" data to not be private, I have to ask. Where is the safest place to host a web server these days?

I've been thinking of putting some data services up, and have no problem with responding to limited court orders, or even paying income taxes on any profits made. I do have a problem with client data potentially being seized without due process."
NASA

+ - Landsat 8 Satellite Successfully Launches into Orbit->

Submitted by adosch
adosch (1397357) writes "The Landsat Data Continuity Mission is now in orbit, after launching Monday from Vandenberg Air Force Base in Calif. After about three months of testing, the U.S. Geological Survey will take control and the mission, renamed Landsat 8, will extend more than 40 years of global land observations critical to energy and water management, forest monitoring, human and environmental health, urban planning, disaster recovery and agriculture."
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Mars

+ - 71 Percent of U.S. See Humans On Mars By 2033-> 2

Submitted by
astroengine
astroengine writes "In a recent poll funded by the non-profit Explore Mars, 71% of respondents agreed that the US will send a human to Mars within the next two decades. Unfortunately, on average, the sample of 1,101 people surveyed thought the US government allocated 2.4% of the federal budget to NASA — in reality it's only 0.5%. With this in mind, 75% of the respondents agreed/strongly agreed that NASA's budget should be increased to explore Mars through manned and robotic means."
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Government

+ - More on missile defense: will the Ground-based Midcourse Defense ever work?->

Submitted by Lasrick
Lasrick (2629253) writes "Kingston Reif analyzes GMD (Ground-based Midcourse Defense) and shakes his head over the House Armed Services Committee (last year) authorizing the Pentagon to spend $360 million more than it asked for to expand the flawed system. "The Committee also provided an additional $100 million to begin deploying existing ground-based or SM-3 interceptors — not the interceptors recommended by the National Research Council — on the East Coast of the United States by the end of 2015 to defend against potential future long-range ballistic missiles launched from Iran.""
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Java

+ - Yahoo! Pushing Java Version Released in 2008->

Submitted by futhermocker
futhermocker (2667575) writes "From TFA:

"At a time when Apple, Mozilla and other tech giants are taking steps to prevent users from browsing the Web with outdated versions ofJava,Yahoo!is pushing many of its users in the other direction: The free tool that it offers users to help build Web sites installs a dangerously insecYahoo! has offered SiteBuilder to its millions of users for years, but unfortunately the tool introduces a myriad of security vulnerabilities on host PCs.SiteBuilder requires Java, but the version of Java that Yahoo! bundles with it isJava 6 Update 7. It’s not clear if this is just a gross oversight or if their tool really doesn’t work with more recent versions of Java. The company has yet to respond to requests for comment."

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"Consistency requires you to be as ignorant today as you were a year ago." -- Bernard Berenson

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