Windows 8 may be the next Vista, but I think the perspective of most people commenting on this story is skewed. As is normal for human beings, ones existence generally alters ones perception.
I work in a large organization, developing software (primarily) and performing IT support duties (secondly). I think the paradigm shift that Win8 introduces is actually a positive thing for users like ours!
Watching 90+% of our users; they're already self-imposing all of the "restrictions" of Win8. If we "took away" multi-tasking, it'd barely be noticed at most desks. Most users here open a single program (full screened), use it, close it, and open the next, sometimes going back and forth between applications by fully exiting the prior app several times! Most users don't truly take advantage of window arrangement, tiling or cascading. Things like copy/paste and minimize are still *advanced* to them. For people who don't live and breathe computers, simple is better. Focus on a single task at hand! So the model that Win8 presents is almost easier, and certainly no more difficult than the way I see things rolling on down the road currently! In fact the full screen start menu, etc, actually brings a level of focus, that I think makes the computer easier for basic users.
Now as a developer, fuck no. I will continue using Windows 7 for a while at least. I run 3 monitors, and arrange dozens of windows to make software development easier. For it's integration, between phone tablet and PC, I will definitely use Win8 casually. I'm actually excited about the platform integration between phones, tablets, Xbox and PCs!