Not at all. Airline statistics tell a big story. They are incredibly safe now. Not too many computers are flying the plane into a mountain.
Wow, I lol'd at this... How could you possibly compare these two? Airspace has an incredibly consistent, standardized and mostly centralized air-traffic control system. you have ~7,000 aircraft simultaneously in the entire US Airspace. We have over 242 Million registered vehicles in the United States. I couldn't find data on how many are in operation simultaneously, but I think it is safe to say you can find over 7000 in operation simultaneously during rush hour in any average city on the interstates there alone.
Add to that the room/flexibility to maneuver in a vehicle on a road system, parking lot, parking garage, shoulder, dirt road, etc. compared to "air space".
Both have weather hazards, granted. Except that often when weather is rough, planes don't fly there (route around it). Motor vehicles don't work that way.
I'm sure I have BARELY scratched the surface here. Maybe we should instead be debating what I meant by "quite a long time". I'd say a significant number of autonomous vehicles in operation in the U.S. is at least a decade away, maybe two.