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Medicine

Scientists Find New Target For Alzhiemer's 107

Posted by kdawson
from the good-news-i-forget-why dept.
GarryFre writes "Neurological researchers at Rush University Medical Center have found a new therapeutic target that can potentially lead to a new way to prevent the progression of Alzheimer's disease. The target called neutral sphingomyelinase (N-SMase) is a protein which, when activated, can cause a chain of reactions in the cell leading to neuronal death and memory loss. Already a substance has been found that shows some promise in halting the progression of the disease."
Graphics

Wolfenstein Gets Ray Traced 184

Posted by Soulskill
from the ach-mein-framen dept.
An anonymous reader writes "After showcasing Quake Wars: Ray Traced a few years ago, Intel is now showing their latest graphics research project using Wolfenstein game content. The new and cool special effects are actually displayed on a laptop using a cloud-based gaming approach with servers that have an Intel Knights Ferry card (many-core) inside. Their blog post has a video and screenshots."
Open Source

+ - Oracle, NetApp drop ZFS patent suit->

Submitted by Anonymous Coward
An anonymous reader writes "It seems Oracle and NetApp has kissed and made up over the ZFS patent lawsuit. Before Oracle acquired Sun Microsystems, NetApp sued Sun claiming ZFS infringed on its patents. Sun the later sued NetApp back. From today all is forgotten and Oracle and NetApp are friends. NetApp CEO Tom Georgens even said the two companies have shared a "common vision" focused on providing solutions that reduce IT cost and complexity. Both companies now want collaboration between them to continue."
Link to Original Source
Hardware Hacking

iFixit Moves Into Console Repair 75

Posted by Soulskill
from the red-ring-of-rebirth dept.
sk8pmp writes with news that iFixit, a website known for Apple gadget teardowns and repair guides, is expanding into the game console market, launching a series of troubleshooting and repair guides to help gamers fix their own machines. They're also starting to sell replacement parts and the tools necessary to work on them. "Right now there are repair guides for 24 gaming consoles, including 206 repairs and upgrades. Some of these fixes deal with major issues, such as the infamous Red Ring of Death from the Xbox 360, but others are simpler. For instance, right now there is no easy way to clean out the fans inside your console. 'I think this is probably the number one cause of overheating these days now that manufacturers have mostly gotten their act together,' Wiens said. 'This is routine maintenance, and it's mind-boggling that the manufacturers don't provide people with an easy way to open the case up and blow it out.' You'll also learn how to replace broken LCD screens on your portables, replace the motherboard on your PlayStation 3, and do just about anything else you might want to do to these systems, from the simple to the harrowing."
Image

Darth Vader Robs Long Island Bank 190

Posted by samzenpus
from the I-find-our-lack-of-funds-disturbing dept.
Apparently the destruction of the second Death Star has stretched the Galactic Empire's coffers so thin that Lord Vader himself is robbing banks. From the article: "Impotent Rebel Alliance security forces tell Newsday (paywall) that Vader marched into a Chase bank in Setauket around 11:30 a.m. today. Brandishing a completely unnecessary handgun — as he had the power to choke the oxygen out every teller's throat — the fallen Jedi demanded cash."
IT

Managing the Most Remote Data Center In the World 98

Posted by kdawson
from the talk-about-latency dept.
blackbearnh writes "Imagine that your data center was in the most geographically remote location in the world. Now imagine that you can only get to it 4 months of the year. Just for fun, add in some of the most extreme weather conditions in the world. That's the challenge that faces John Jacobsen, one of the people responsible for making sure that the data from the IceCube Neutrino Observatory makes it all the way from the South Pole to researchers across the world. In an interview recorded at OSCON, Jacobsen talks about the problems that he has to face (video), which includes (surprisingly) keeping the data center cool. If you're ever griped because you had to haul yourself across town in the middle of the night to fix a server crash, this interview should put things in perspective."
Science

+ - Microneedle Patches Improve Vaccinations->

Submitted by ElectricSteve
ElectricSteve (1655317) writes "Doctors have been using hypodermic needles for more than 150 years — but syringe vaccinations could be just about to be replaced by a simple patch you can stick on your arm with no medical supervision. The microneedle patches have an array of microscopic needles on them that penetrate the skin just deep enough to dissolve and deliver a vaccine without causing any pain. There's no sharp hazardous waste left over, they're no more expensive than a syringe, and most importantly, tests on mice are showing that microneedle vaccinations are significantly longer-lasting than deeper injections delivered by syringe."
Link to Original Source
Games

+ - UK games magazine 'PC Zone' to shut after 17 years-> 1

Submitted by davidmcg
davidmcg (796487) writes "BBC News reports that UK games magazine, PC Zone, is to close after 17 years of publication. This seems like the end of an era for people who's first encounter with PC games was in the 90s with hits such as 'Syndicate' and 'Doom' etc. PC Zone will be a sadly missed magazine with it's quirky reviews and sometimes irreverent and off-beat humour."
Link to Original Source
XBox (Games)

Anatomy of an Achievement 157

Posted by Soulskill
from the you-don't-get-an-achievement-for-commenting-on-this-one dept.
Whether they annoy you or fulfill your nerdy collection habit, achievements have spread across the gaming landscape and are here to stay. The Xbox Engineering blog recently posted a glimpse into the creation of the Xbox 360 achievement system, discussing how achievements work at a software level, and even showing a brief snippet of code. They also mention some of the decisions they struggled with while creating them: "We are proud of the consistency you find across all games. You have one friends list, every game supports voice chat, etc. But we also like to give game designers room to come up with new and interesting ways to entertain. That trade-off was at the heart of the original decision we made to not give any indication that a new achievement had been awarded. Some people argued that gamers wouldn't want toast popping up in the heat of battle and that game designers would want to use their own visual style to present achievements. Others argued for consistency and for reducing the work required of game developers. In the end we added the notification popup and its happy beep, which turned out to be the right decision, but for a long time it was anything but obvious."
PC Games (Games)

Valve Releases Updated Alien Swarm For Free With Code Base 164

Posted by Soulskill
from the game-over-man-game-over dept.
baronvoncarson tips news that today Valve released an updated version of Alien Swarm, a popular Unreal Tournament 2004 total conversion mod. The creators of the mod were hired by Valve, and they've helped turn it into a stand-alone game running on the Source engine. Valve is also releasing the code base for Alien Swarm and an SDK. The game is available for free on Steam.
NASA

NASA Revamps Historic 4-Million-kg Mars Antenna 66

Posted by Soulskill
from the we're-gonna-need-a-bigger-bumper dept.
coondoggie writes NASA is working on some difficult renovations to reinvigorate its 70-meter-wide 'Mars antenna.' The antenna, a key cog in NASA's Deep Space Network, needs about $1.25M worth of what NASA calls major, delicate surgery. The revamp calls for lifting the antenna — about 4 million kilograms of finely tuned scientific instruments — to a height of about 5 millimeters so workers can replace the steel runner, walls and supporting grout."

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