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Comment Re:Magnetogenetics (Score 1) 70

That might be blowing the effectiveness of the tool out of proportion a bit. For one thing, "memory" is spread over numerous regions of the brain, among hundreds of different neuronal and non-neuronal cell types. Simply affecting one type via magnetogenetics would likely not have too much of an impact on something this complex. However, stimulating dopamine neurons in the substantia nigra of a parkinsons patient using a tool such as this would theoretically restore motor function similarly to deep brain stimulation (which currently has FDA approval). Erasing memories may not be a bad thing either. Think of all the help that could be given to PSTD patients...

Comment Magnetogenetics (Score 1) 70

An alternative technique to Optogenetics is called Magnetogenetics, which in my opinion may have even more clinical relevance. In optogenetics, viral vectors are used to transfect the opsin of choice in the neuronal population of choice, and then those neurons can be stimulated by the wavelength of light specific to that opsin. The newer and less well known technique of Magnetogenetics, uses viral vectors to transfect a specific ion channel that opens in response to magnetic stimulation of a certain frequency (see http://www.nature.com/nnano/journal/v5/n8/fig_tab/nnano.2010.163_F1.html). This means that once the virus was injected and the new receptor in place, stimulation can be done with a "magic wand" type stimulator, and wouldn't require fiber optics to be implanted in the brain or mounted to the skull. This would be considerably easier to use from a treatment perspective, and would have less room for hardware failure, etc. Of course, it would also be easier for a non-medical professional to activate such a system... Clearly more work needs to be done in both fields, and it's certainly an exciting time to be in neuroscience!

Comment Fun ways to save cash: (Score 5, Insightful) 699

On top of outsourcing Sun employees, I think one of the big money savers for IBM was laying off approximately 5000 of their own employees just a few months ago. I guess they needed the cash to buy Sun, so they could outsource Sun's employees to save more cash... This hardly seems like good corporate policies in our current economic climate. I just don't see how average Americans tolerate companies who fire 5000 of their own (American) employees to raise enough cash to buy another company to increase their stock margins. Isn't this the sort of business policy that got us into this recession?

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