In my eyes, GITS provides a very deep reflexion on the nature of what might become.
In particular, it has been a pioneer in issues such as transhumanism, the impact of AI vs biological intelligence, the nature and value of interpersonal relations, the changes in the notion of self and identity in a world where you can change your body as if it were a utility, and the cutural impact of "dehumanization".
I sincerely hope Spielberg can capture the depth of the movies and series.