The bias is subtle and I imagine unintentional. It is simple things like "the Republican senator from Alaska Ted Stevens has been found guilty...." vs. "The Illinois governor has been charged with....."
The most obvious case was when Bush was first elected and he and Clinton were at the same function. "President Clinton and Mr. Bush were at ....." It also shows up in story selection. Every Palin slip was replayed gleefully over and over. Biden slips were somehow never mentioned. I didn't vote for either but it was pretty clear who they liked and didn't like.
I should mention that I listen to NPR daily and thoroughly enjoy them. I just take everything they say and run it through my bias filter. I do find it irritating when someone claims they are unbiased. In a way Rush and Hanity are more honest. They never claim to be unbiased. I find it best to get your news from a variety of sources.