There are two cases which are in contradiction on this point. The first is Vernor vs Autocad, where it was found that when you buy a copy, you do indeed become the owner of that copy in one particular sense which is relevant to installation of software (as we will see). The second case is Blizzard, in which it was found that you do not become the owner, but are only the licensee.
The sense in which you need to be the owner is that of Title 17 Section 117. If you are the owner of a copy in that sense, you have the right to both make any copies or adaptations essential to use with a machine, and you also have the right to authorize others to do so on your behalf.
Blizzard found you are not the owner in the sense needed. The implication of only being the licensee and not the owner of a copy is that you need some permissions from the owner of the copyright in order to make copies. It is established law since MAI that when you load software into memory to run it, you are making a copy in the sense of the copyright legislation in the US. It is not so clear that this is true outside the US, which may be important.
The permissions given, according to Blizzard, are given in the EULA. It follows that if you break any EULA condition, you no longer have permission to copy, and so your next use will be in breach of copyright. This means that not only can you be sued by the owner for breaching a civil contract with him, which you entered into by click through. You will also be subject to prosecution for breach of copyright, which is a criminal offense.
It follows that breaching the EULA in ways that have intrinsically nothing to do with the act of copying can put you in breach of copyright on subsequent use. If, for instance, the EULA says that you will not have on your computer or install in future a copy of mdbtools, whether this is relevant or not to the software you are installing, then if you do, you are in breach of copyright. Even if what you are installing is, for instance, a calculator program, or a photo retouching program, or a calendar, or whatever. If the EULA says you must wear a particular uniform, be under a certain weight, be of a certain racial or ethnic or religious background, if you use it not being or doing any of those things, you are in breach of copyright.
The Church of Scientology could, for instance, put in the EULA that a freely sold copy of some software was only to be used by paid up members of the Church, and anyone who used it would then be in breach of copyright if he either was not in or had left the Church. Political parties could license material to their members and ban non-members from looking at it.
Remember, its the act of loading into memory that is copyright violating now, not the act of duplicating and distributing. This is because if Blizzard is the binding precedent, the protections of Section 117 no longer cover use of software by a buyer of a retail copy.
On the other hand, if Vernor is the binding precedent, then you are the owner of the copy, and you have S117 rights to do any adaptations necessary to use it with a machine. A machine. This means, if its OSX, the machine of your choice. You will then be liable to civil suit by Apple for breaching the civil contract of the EULA, but you won't be in breach of copyright.
All this has no bearing whatever on the GPL. If you are the owner of a copy, you are only exempted in terms of further copying and the making of derivative works by S117, and this only covers use with a machine. A machine. Not machines, not any particular brand of machine. A machine. One machine of your choice, unless given other permissions.
This means that the GPL sections which regulate what you may do in the way of copying, making new works with, distributing, remain valid. It is a common piece of Cupertino FUD to say that if Apple loses the power to restrain installation of OSX to its own brand of computers, the GPL falls. It does not.
All that falls is Apple's power to sell at retail software than can technically be installed on any brand of machine, while restraining it by either copyright or by EULA clause or both to being installed on its own branded machines. That will not affect the GPL. MS OEM contracts, upgrades, or indeed any other company in the industry besides Apple, because no other company engages in such a bizarre practice.