Comment Heart Shell (Score 1) 258
TFA contemplates using either cadaver hearts or non-human (pig is the readily available animal with a compatible sized and structured heart). De-cellularizing those would remove the antigens that trigger rejection. Then using compatible stem cells to create a new histocompatible heart using the old framework. Pop into the patient.
Currently we use a de-cellularized pig heart valve as an implant. The patient's own cells invade the matrix and set up housekeeping, very much the way the fetal cells did in this demonstration.
One other advantage would be that the new organ would be 'young', not whatever age the donor might have been.