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Biotech

Submission + - Stem Cells Shown to Protect Dying Motor Neurons

Penguinshit writes: "Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease characterized by rapid loss of muscle control and eventual paralysis due to the death of large motor neurons in the brain and spinal cord. Growth factors such as glial cell line derived neurotrophic factor (GDNF) are known to protect motor neurons from damage in a range of models. Human cortical neural progenitor cells derived from fetal tissue (ie. stem cells) can be expanded in culture for long periods and survive transplantation into the central nervous system, in some cases making large numbers of GFAP positive astrocytes. They can also be genetically modified to release GDNF and thus act as long-term 'mini pumps' in specific regions of the brain. In this study a team at UW-Madison's Waisman Center genetically modified human neural stem cells to release GDNF and transplanted them into the spinal cord of rats with mutant SOD1. Following unilateral transplantation into the spinal cord of the rats there was robust cellular migration into degenerating areas, efficient delivery of GDNF and remarkable preservation of motor neurons at early and end stages of the disease within chimeric regions.

This work is especially important to me, as I have been living with ALS for almost three years."
Hardware Hacking

Submission + - ICE cracks down on mod chips (ice.gov) 1

rifter writes: Today US Immigration and Customs Enforcement (ICE) led a massive raid over 16 states in order to arrest people who were allegedly engaged in the importation, installation, sale, and distribution of mod chips and swap discs for Sony's Playstation 2, Microsoft's XBOX and XBOX 360, and Nintendo's Wii.

I did not find a link to the CNN story but the talking heads there were claiming that just having or installing a mod chip was a felony punishable by 5 years in jail and a $500,000 fine, presumably due to the claim that these activities violate the DMCA, as stated on ICE's site. The best news of all is that there is more to come. ICE says this is part of an expanding program of IP enforcement. As they say:

"Illicit devices like the ones targeted today are created with one purpose in mind, subverting copyright protections," said Julie L. Myers, Assistant Secretary of Homeland Security for Immigration and Customs Enforcement. "These crimes cost legitimate businesses billions of dollars annually and facilitate multiple other layers of criminality, such as smuggling, software piracy and money laundering."

Obviously the many legitimate reasons for using the MOD chips (backups, foreign titles, etc.) are ignored here. So remember, kids, when you mod your Xbox the terrorists win! I guess it's a good thing for the US arm of Hezbollah they focus on fake Viagra and cigarettes. Dealing in modchips might get them caught more often.

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