When they decided to start hiding or removing useful settings while adding so much bloatware into it that they might as well have renamed it FireIE 6.0, I quit using it for daily browsing habits.
Now that it is up to version 25+ (which is fucking stupid in its own right, trying to play version catch-up with Google just because), I still find that I don't use it for anything but Twitch.tv and Disqus.
For some reason the chat interface for Twitch never loads in Chrome no matter what I do, and Disqus comments never load in Chrome no matter what I do.
Not that I interactively use the Twitch chat, since it requires a Facebook account to post, but I can at least read the commentary and maybe send the developers a more full-fledged response via email when I am watching something from Digital Extremes or Trion for instance.
As for Disqus, I can't figure out what it is - it may be Chrome mangling the Disqus cookies in some way or hating the number of redirects the Disqus system itself uses when logging in and loading comment sections, but it just sits and spins and never loads. Loads instantly on IE10 or Firefox though (yes, I use Windows 7 exclusively at the moment).