I'm more concerned about this trend to solder RAM onto boards (Apple, I'm looking at you here.) -- RAM goes bad over time -- a shockingly short time. (google the papers (by google) about RAM failure rates, and what they do after 18 months). After a couple of years error rates go up -- way up. (ECC would very definitely be your friend here, but intel only makes it available on xeon series chips (the circuitry is there but fused off in consumer grade chips) )
My experience has been that after 24 months, you should just toss the ram dimms in the trash and start with new ones -- and you might as well max out the ram at that point. Otherwise the machine starts getting flaky as soft and uncorrected errors happen with increasing frequency.