Left Pants Pocket: Primary car key + house key.
Right Pants Pocket: Car Key + house key, and key to brother-in-law and sister's house. And a separate key ring with garage key, 2 keys to get into my place of employment and my office there, and one mystery key that I've had for 25 years. What it opens is a dim memory long lost in the past. I keep it out of sentimentality or maybe laziness. Also have a RFID card that accesses some doors at work.
In my office: All the other keys needed for various secure areas, desk, file cabinets, lock-out devices, et cetera. They never leave work.
In my home: All the other keys needed for file cabinets, bike, tool shed, my arsenal (gun safe). They never leave the house.
Note: I will NOT get locked out of my car or my house, hence the two sets of keys. The car keys (late model Jeep) are embedded in a keyless entry fob-thing. A pretty potent weapon, if you think about it and if you need it. And if I don't have ready access to my, um, arsenal.