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Comment Re:I kinda agree with him (Score 1) 1153

Why stop with Calculus? The path of modern medicine is being decided by people who can't tell a stem cell from a potato, or tell the difference between genes and jeans. We have epidemics of diseases that were largely eradicated because people aren't getting vaccinations. And we have lawmakers and voters deciding on nuclear energy and chemical waste disposal who haven't the slightest idea about what they're deciding. Calculus won't help that.

Comment Re:Not much literature either (Score 1) 1153

I don't know about the deep meta-analysis, but I agree that scientific papers use many of the same skills as literature. Having written more than my fair share of published scientific papers, and having been on the other side as a reviewer quite a few times, I can't stress how important it is that a manuscript needs to tell a damn story. It needs to have a point, and each paragraph needs to sell the reader on that idea. Perhaps it's not Dickens, but a paper that doesn't tell a story that the reader can follow ends up on the scrap heap in a hurry.

Comment Re:The Rain Mouse? (Score 2, Interesting) 259

There are plenty of brain issues that aren't well modeled in mice, such as anything involving the prefrontal cortex (the front of the brain, where most of the higher-order thoughts reside). Mice just don't really have a true prefrontal cortex, which is where we do much of our higher-order thinking. The cousin of this gene, RGS4, showed up as a candidate gene for schizophrenia; mice lacking the gene are largely unaffected. The same case is true for most mouse models of psychiatric disorders, for that matter.

Also, there's not that much literature on RGS14 at this point (it doesn't seem to have come up in any of the GWAS -- wide scale genome association studies) for psychiatric disorders, but it has been identified in molecular studies as a target of P53 (a central cancer regulatory mechanism). It would not be out of the question for this knockout to have a significant increase in cancer risk (brain or elsewhere), but not have this detected in a small-scale study.

Comment Re:Too bad we don't have rules to deal with this (Score 1) 839

I don't brake at every green light, but I do sometimes wait a half a second or two when the light turns green to make sure that the dumbasses have finished running the red light, rather than just jump on the gas and get t-boned. Are you the type that is in the car behind me laying on the horn 0.01 milliseconds after the light turns green, or indignant that I don't make a left turn in the path of an oncoming cement truck?

Comment Re:Why Are We Deferring to an Economic Organizatio (Score 1) 715

And for some reason, we're not demanding they open the sequencing data on the cancer gene we just accepted that story and we trusted those scientists.

Are you sure we're not? I haven't seen a published genomics paper in years that doesn't have the raw data accessible in some form. It's a requirement for most major journals, as well as from most funding sources. If you want to publish, you release the data.

I agree with you that every moron thinks they can analyze the climate data better than the entire field of climatologists. Relatively few people think they understand particle physics better than the people at CERN; but somehow everyone thinks they're an expert on climate change after reading a few headlines that they instinctively disagree with (although they don't actually understand). Science is rarely a good spectator sport.

Comment Re:Sh..... (Score 1) 534

Some of them, yes, were certainly the "best and brightest". The problem isn't with the personnel in the military that are operating this technology, it's with the corrupt procurement system. These systems were designed and built by the big defense contractors, and they were paid handsomely to do so. There's no incentive for them to be cost-effective, or to go above the minimum requirements. Heck, if they don't meet the minimum requirements they'll get a new contract to fix their mistakes in a few years. These systems take so long to get in place that they're outdated by the time they hit the ground. And the way they are designed, spec'd, and implemented means that simple updates take years and billions of dollars.
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The Perfect Way To Slice a Pizza 282

iamapizza writes "New Scientist reports on the quest of two math boffins for the perfect way to slice a pizza. It's an interesting and in-depth article; 'The problem that bothered them was this. Suppose the harried waiter cuts the pizza off-center, but with all the edge-to-edge cuts crossing at a single point, and with the same angle between adjacent cuts. The off-center cuts mean the slices will not all be the same size, so if two people take turns to take neighboring slices, will they get equal shares by the time they have gone right round the pizza — and if not, who will get more?' This is useful, of course, if you're familiar with the concept of 'sharing' a pizza."

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