I once interviewed for one of the big investment banks (not gonna give a name, but its one of the big evil wall street banks that everyone knows about). That one has the usual silly "4 year degree with 3.0 GPA or we don't even talk to you, no exception, not even if you're a well known superstar in the software world" rule.
I didn't know that, and I only have a 3 year degree (from a country where thats common). I aced the interview as that particular job wasn't even very computer science-ish, and they had been looking for someone for months to fill that position. Then they noticed the little issue of me not having the mandatory degree.
The hiring manager (not someone from an agency, but someone on their payroll) just modified my resume without telling me and passed it over to HR for final signoff. I got hired.
Fast forward a year, they're updating the HRIS system and verifying that all the info is correct. I get an email from HR asking me to confirm that I indeed have a 4 year bachelor with 3.0 GPA from Big Name College XYZ with my boss CCed.
My boss quickly replied, before I had time to go "WTF?!", that I indeed had such a degree.
Needless to say, him and I had a little talk afterward. That was awkward.