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Comment Re:Be careful with those assumptions. (Score 1) 281

By active gene manipulation through selective breeding.

True, and that is why we've made so much progress in such a short period of time with pigs. However, to assume that natural selection cannot accomplish in 4000 years, what we've done through selective breeding in ~40 years is odd to me. In humans there isn't some intelligence applying the selection, but that does not mean that selection is not taking place. The difference is that the environment, consisting in part of the food that can be cultivated in that environment, is applying the selection pressure. Most humans can utilize lactose well into adulthood because we evolved the ability to do so because the offspring of humans who could were more likely to survive and breed. The ability to digest lactose as an adult is not as advantageous as it once was, and in the absence of that selective pressure the trait is becoming less universal. Both the historical spread of lactose tolerance and the current rise of lactose intolerance are examples of evolution in action.

What we HAVE been able to do by avoiding eugenics with humans while applying modern medicine is to make less robust humans

No, humans are not less robust, at least in an evolutionary sense, because evolution is all about survival in the environment as it is at the moment. It is not about some theoretical ideal or past conditions that no longer apply. It is inconvenient that one my sons is lactose intolerant, sure, but he lives in a time and place where the ability to digest lactose does not affect his long term prospects of reproduction appreciably. Similarly, it would have been nice for early sailors to be able to synthesize vitamin C on their own, but they couldn't and that led to a lot of brave men suffering and sometimes dying of scurvy before they realized that eating citrus fruits or extracts can prevent it (even before medicine realized what it was about citrus that prevented scurvy). Humans have always used our intelligence to think our way out of apparent maladaptions to our environment. The net effect has been to show that our greater intelligence is a more valuable adaptation that big teeth, claws, and a vitamin C synthetic pathway in the liver.

...has kept people with bad genes alive...[emphasis mine]

There are no "bad" genes. There are traits which are not well adapted to a particular environment or situation, but that does not make them bad per se. Sickle cell being the poster child for an apparent disorder this actually advantageous under certain conditions. Same goes for white skin, and advantage that evolved and spread in colder northern europe, but is a hindrance to whites living in regions with plenty of UV exposure throughout the year because it increases your risk of developing cancer. All traits are trade offs and to assume any trait is inherently "Bad" is to fall into the same faulty reasoning that led to eugenics in the first place.

What you are seeing is the survival of detrimental mutations or maladaptations, not natural selection against them.

Evolution is not directional. There is not De-Evolution as a counter to Evolution. There may be a future environmental condition where the current maladaptation are favorable. Evolution is the accumulation of genetic changes over time, its not the accumulation of abilities like in an RPG. Shortly after humans evolved tricolor vision we started loosing the ability to detect most pheromones. It is believed that this loss of a previously essential ability occurred because the evolutionary role for which pheromones had evolved (to signal sexual receptiveness among other things) could also be met by increased color sensitivity (consider the baboons with the red asses everyone likes to laugh at, or the ones with the blue, red and white skin on their faces), thus making the loss of one specific ability unimportant in the large flow of genetic changes.

My original subject line still holds be careful with those assumptions

Comment Re:Be careful with those assumptions. (Score 1) 281

Researchers have been studying human evolution by tracking changes in our DNA and using advanced modeling techniques to gauge the rate of our evolution, including projecting various changes backward in time. That's how we know that Neanderthals and modern humans bred with each other. We've found the Neanderthal genes in the modern human population. Most genes contribute to more than one trait, so even small changes in our DNA can lead to large changes in our phenotype. To assume that somehow those changes have magically skipped over affecting any of the numerous genes involved in ingestion, digestion, and metabolizing our food is asinine.

Our ability to support the energy sink that is the human brains is dependent upon our ability to get enough nutrients, and more importantly energy, to support its development and high maintenance requirements as an adult. That it self is evidence of our diet and bodies evolving together. Also, the reduction in the size of our jaws, leading to chronic problems with impacted 3rd molars, is another instance where we have evolved as a result of our diet. The larger jaws of earlier hominids are not necessary because we cook our food. That cooking makes the nutrients more available, meaning we need to eat less. It also makes the food softer, meaning we don't need massive jaws to constantly grind seeds and roots and raw meat.

There is plenty of other evidence that our bodies have evolved in large part BECAUSE of changes in what we eat and how we prepare it. The problem is that fad dieters have never been very big on reading peer-reviewed literature. They prefer to read the book-of-the-month endorsed by some celebrity or health guru.

Comment Be careful with those assumptions. (Score 0) 281

The idea that we have not had time to evolve to farmed food is just stupid. We've managed to completely revamp the modern pig phenotype from a slow growing lard producing machine, with back fat measuring as much as 9-12 inches to a pig where the standard backfat thickness is measured in millimeters in less than half a century. Humans have been farming for roughly 100 times longer than that.

We've seen human populations with distinct difference in their ability to handle different components of foodstuffs (lactose, gluten, fat, etc). Explain to me how that ISN'T evidence of evolution! The whole "paleo" fad is based on two false assumptions. 1) that we are no longer evolving, and 2) that evolution is directed at some idealized collection phenotypes.

Comment Re: Ask about everything (Score 1) 53

I don't care what you want to put in your body. I expect the same respect from you.

Wow, you have a very carrying soul [/sarcasm]

Unlike you, the FDA has a statutory obligation to make sure that foods and drugs sold in the US are safe for their intended use. The "intended use" part allows for a surprising amount of wiggle room. How is the FDA to know if you bought vitamins to treat some disease (a drug use) or to make sure you meet the normal RDA (not a drug use)? They can't and don't try. The intended use limit is not on the end user, but the seller. VitaminsRUs cannot advertise that their vitamin pills prevent cancer, but if you believe they will there is nothing the FDA can do to stop you, and they won't even try.

You do not have the moral authority to tell another person what they may or may not ingest.

The FDA is not a moral authority, but a scientific one. They are staffed with experts in various fields necessary to decide which products are safe and effective, and which are not. You appear to feel yourself up to the task of sorting the wheat from the chaff, but most Americans are not. I'm going to go out on a limb here and guess that you consider yourself to be of above average intelligence and education (ironically, the vast majority of people do as well). But think about most of the people you see in a day (neighbors, friends, family, strangers). How many of them would you suspect are similarly equipped to handle sophisticated marketing made to give the appearance of scientific validity despite a demonstrable lack there of? That is why the agency was created (see patent medicines, most of which were simply different forms of cocaine). To protect the largely ignorant populace from unsafe and unproven products.

As I stated before: regulation to ensure the product contains only the labeled, unadulterated ingredients is the limit. I can also conceptually support banning "false claims" but that is a very squishy concept in biomedical terms and is typically advocated as an subterfuge to ban things.

All such regulations require oversight. Verification that companies are obeying the laws that are supposed to govern their actions. The dietary supplement market is exempt from much of this oversight because they lied to the US population and convinced them that the FDA was out to take away their vitamins and make they by prescription only. That would never have happened. I know this because I do regulatory work with the division of the FDA involved in regulating the animal equivalent to dietary supplements, namely Feed Additives. No prescription is needed for an approved feed additive, no consultation with a veterinarian is required, but feed additive manufacturers are required to prove that a new additive is safe and effective. Once approved, anyone can sell that feed additive for the approved use without further involvement of the FDA. A feed additive petition takes about 2 years (on average, with a HUGE SD due to a non-normal distribution) from submission to approval, but once the approval is made no more work is required. In most other countries the requirements are similar, except that approvals are vendor specific (Company A and B both have to register their Vitamin C), and have to be renewed periodically (US system only requires approval once).

Comment Re: Ask about everything (Score 1) 53

FDA regulations are use based. If you are taking vitamin C as a way to meet your daily requirement for vitamin c, then there is no health claim and your purchasing experience wouldn't change. However, the vitamin c seller would need to convince the FDA as to their supplements efficacy of disease prevention, which is BS anyway. The FDA oversight wouldn't do much to vitamin availability (the strawman the afore mentioned misinformation campaign used to drum up support for thei dietary supplement exclusions), but it would keep the "Magic" (read bullshit) pills Dr Oz keeps pushing off of the market in the first place. It would also cause other known BS like herbal supplements that lack any of the advertised herb, or the homeopathic sugar pills to be pulled due to a demonstrable lack of efficacy.

Comment Re:Ask about everything (Score 3, Informative) 53

The really frustrating part is when people who will rant against drug companies and a supposed lack of testing (which could not be further from the truth) will in the same breath rave about the latest dietary supplement (for which no testing is actually required, and over which the FDA has little legal oversight).

The food supplements industry is largely unregulated in the US due to an impressive mis-information campaign back in the 1980's which resulted in a special section of the regulations for dietary supplements. Animal feed is more tightly regulated than feed supplements. Feed additives have to prove, to the satisfaction of the FDA, that they are effective for a specific purpose. No similar requirement exists for dietary supplements.

Comment ErnieKey obviously has no knowledge of US farming (Score 1) 133

If ernieKey knew anything about modern agriculture he wouldn't have claimed such a lack of technological progress in agriculture. Crop production uses GPS controlled tractors and combines, animal production uses computer controlled monitoring and automation of environmental controls, electronic feeding systems that allow for group housing AND individualized nutrition plans, feed mills use real time NIR to evaluate feedstuffs so as to enable more accurate feed formulation, slaughter houses are wonders of automation where a carcass can be processed with a minimum of human interaction... I could go on indefinitely. As neat as his techno be, the tech already in widespread use in the industry is similarly impressive (and shipping TODAY).

Comment Re:The science behind GMOs show they are safe. (Score 1) 272

Likewise, "companies must submit studies, and the FDA must approve them, before a genetic change may be added to a food" sounds equally reasonable and yet is labeled "zealotry" by folks like the parent poster.

As a matter of fact, the FDA is already one of 3 federal agencies in the US responsible for oversight of GMO:

What gets everyone all hot and bothered (myself included) is the erroneous perception that GMO are not regulated at all, or that they've been confirmed as unsafe for people or the environment despite all of the evidence being in opposition to that position. It is decidedly anti-science zealotry that prevents many from accepting that the scientists involved in developing and certifying GMO's have done their jobs, and done them well.

Comment Re:I actually read the article... (Score 1) 272

There is a specific allergen (short protein sequence) in peanuts that is responsible for the peanut allergy. It is well known which DNA sequence results in the offending protein sequence. Therefore, the DNA inserted into the new GM crop is compared via computer against all known allergens (not just the peanut allergen) based on the DNA and protein sequences. They also look for sequences that are similar to known allergens so that more involved testing can be done (cell culture work, anima models, etc.) to rule out the accidental development of a "New" antigen. So far we have had 20 years of 100 percent success in preventing GM crops from introducing new or already known allergens into the food supply. Can't guarantee we won't slip up eventually, but you have to give credit where credit is due.

Comment Re:Wrong (Score 1) 272

Sure it was stopped before commercialization. But this is hardly something you get when splicing.

You are flat out wrong. This is a case of why GM is so safe, and an example of the system working as designed.

Take a look at Solanine in potatoes. As a member of the nightshade family, there is always the potential that a new variety of potato will contain dangerous levels of solanine or other glycoamyloids just due to random interaction between the parent genomes. Bombarding potatoes with mutagens like ionizing radiation, or carcinogenic chemicals are OK by organic standards, and how new varieties of potatoes were developed before we even understood that DNA was the source of inheritance. This kind of genetic modification is MORE likely to result in accidental changes in Solanine concentration because so many genes are changed simultaniously. Several varieties of potatoes that were not GM have been removed from the market only AFTER they made people sick.

The targeted nature of modern techniques mean we can characterize the new strain to a previously impossible level BEFORE they hit the market. Who cares how many mistakes they make in the lab, as long as they STAY in the lab. The 78 UK made sick by Solanine poisoning in Britain in the 1970's are 78 more adverse events than have ever been reported for ALL GM products combined over the last 20 years precisely BECAUSE we scrutinize all new GM strains so closely before they are allowed on the market.

Comment Re:Let's get rid of EU (Score 1) 272

I was in Germany a few weeks ago for work, and my German colleges all seemed to be of the opinion that the EU was never meant to grow past the initial members, at least in the near term. There is a lot of shared culture and history amongst the original EU member states, and it was viewed as the first step toward the type of federalization you mention. However, with the expansion of the EU to include member nations that can only be considered "Europe" if you've had a few fingers of scotch, are standing on your head, and squinting, the pace of such integration gets slower and slower. It's also part of why Greece is in such dire straights.

Used to me that in such a situation Greece could allow their currency to devalue, relative to the rest of Europe, and they'd pull themselves out in a few years as the value of their existing debt is reduced. However, now that their currency is also pegged to the German et al. economies they cannot do that and what would of taken a few years will now take decades.

Comment Re:Misinformation? (Score 1) 493

You have no idea what you are talking about. I'll pit my annecdotal experience against your annecdotal experience.

My sister (1 at the time) got a mild case, but then came down with Shingles while in college. She was in agony for almost a year and considered taking a semester off because she was in so much chronic pain.

My brother got it when he was 3 and had it everywhere. On his genitals, in his mouth, down his throat. He was already a sickly child who did not gain any weight for the 1st 6 months of his life. The sores in his throat exacerbated his respiratory problems and he had to be hospitalzied.

Public health is a numbers game. The cost of the invervention weighed against the cumulative costs on society. A disease does not have to be consistently life threatening to be worth erradicating through vaccination. The cost of treating events like my sisters shingles and my brothers hospitalization have a large effect on the total cost of a disease organism. Much higher than would be expected based on the prevalence of such complications. Take the human suffering component into account and a solid case for vaccination becomes even stronger.

Comment Re:Well... (Score 4, Interesting) 493

What about people with other health conditions who cannot tolerate the vaccine?

They would benefit in the event of an oubreak in there area. They could be notified directly that there was an outbreak in the area so that they could then decide to leave the hot zone before becoming infected. I don't think anyone is claiming vaccines should be administered to those at high risk for adverse events (egg allgies, or previous adverse reactions to similar vaccines). However, unvaccinated people do pose a risk not only to themselves, but to others. Being able to mitigate those risks would help everyone.

To be clear, I approve of something like this for the US (where I live) but only if the list is maintained by health officals only. I see no reason for this to be publicly available information. I have no business knowing if you are vaccinated, but the WHO or CDC does in the event of a legitimate risk in your area.

Beyond a certain critical mass of vaccinations, additional vaccinations are subject to diminishing returns.

Very true, but that critical mass is around 95%. The original article makes it clear that in Canada, the vaccination rates are nowhere near that number. Articles I've read in the US place the rates below that number as well. Especially in regions where non-medical vaccination abstentions are high (religious groups, Wealthy communities suffering from the misconception that vaccines are related to autism, etc.).

Comment Re:Comon.. Really? Robots to move cows around? (Score 1) 65

Your inability to see a reason does not mean one does not exist. Although, I don't disagree regarding the daily contact. However, on the farms I've visited that use robots, their direct human contact is not appreciably lower, it is only the type of interaction that has changed.These cows milk themselves so they are not rushed in the parlor by a hired hand trying to get done with their shift or this particular chore faster, which is interaction the cows are probably better off without. Instead the herdsman has time to walk the pens while he and the cows are more relaxed.

These robots also come with all sorts of sensors and automatic flagging software to notify the producer of potential problems. The sensors in these machines can predict mastitis based changes in the composition of the milk before the cow exhibits any signs that the farmer could detect, they can track milk components on a daily basis per cow, and enable targeted feeding of extra nutrition during milking to supplement the TMR for the highest producing cows. For a modern, data driven dairy, these machines are a treasure trove of information about the cows to supplement the knowledge that comes from working with the cows on a daily basis

Also, keep in mind that robotic milkers don't really scale beyond 500 cow herds. These are a labor saving device for those farms that can least afford to hire another person. Each robot can handle about 60 cows depending on how productive they are. Above 500 cows (8 robots) and it becomes more cost effective to use a traditional parlor with full time employees to do the milking.

This robot, which does look more like a graduate student project than a commercial product, appears to work in an open field. That is a very different application from the moving gates you are referring to. Robots are generally built for a specific purpose, and those automated gates you describe wouldn't do much good for cows spread over several acres, whereas this one might in the future.

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