1. Traffic monitoring built in to my chosen GPS enables changes to route after setting off.
2. Even without automatic traffic updates, I can see problems ahead, turn off the current route and let the GPS pick up the pieces.
3. If I've got a long route memorised (in a hypothetical world without GPS), but somehow forget a turning I will have to backtrack or find signs to the next "waypoint" in my mind. If I'm in another country, or well outside my usual area of travel, that's a non-trivial task.
4. "Safety" camera information is available from the GPS, along with stuff like petrol stations, car parks, etc..
5. Why shouldn't I use GPS? Just because people have done things for about a century doesn't mean we can't embrace progress. I can still read a map quite nicely, thanks and still use one for planning longer walks or driving tours etc. But I would not willingly sacrifice my car's GPS for day-to-day driving.