Want to read Slashdot from your mobile device? Point it at m.slashdot.org and keep reading!

 



Forgot your password?
typodupeerror
×
Biotech

Submission + - The Untold Story of induced Pluripotent Stem Cells (allthingsstemcell.com)

ParadoxDruid writes: "Induced pluripotent stem cells are a hot new stem cell type that is able to become any kind of tissue, offering great potential for treating diseases and injuries. Although they look and act just like human embryonic stem cells, these induced stem cells can be made from adult cells that are reprogrammed to an earlier state and consequently can be patient-specific. What is interesting is that while induced stem cells were created from human tissue only in 2007, they have a decades' old history of theories and experiments that is not often reported."

Comment Re:Still a long way to go... (Score 4, Informative) 126

I recently met Pete Coffey, the lead scientist on this effort (he collaborates with scientists in a research group across the hall from mine), and attended his technical talk on this procedure. You are correct, they're transplanting retinal pigment epithelium. However, they've done experiments with both wet AMD and some preliminary work with reviving dry AMD. Very promising work; but yes, very involved surgery with a success rate of 75% even for ideal patients.
GNOME

OpenSolaris 2008.11 – Year of the Laptop? 223

Ahmed Kamal writes "Is Linux getting too old for you? Are you interested to see what other systems such as OpenSolaris have to offer? OpenSolaris has some great features, such as ZFS and dtrace, which make it a great server OS — but how do you think it will fare on a laptop? Let's take an initial look at the most recent OpenSolaris 2008.11 pre-release on recentish laptop hardware."
Privacy

New Bill To Rein In DHS Laptop Seizures 311

twigles writes with news of a new proposed bill that seeks to curtail DHS's power to search and seize laptops at the border without suspicion of wrongdoing. Here is Sen. Feingold's press release on the bill. The new bill has more privacy-protecting safeguards than the previous one, which we discussed last month. "The Travelers Privacy Protection Act, a bill written by US Senators Russ Feingold, D-Wis., and Maria Cantwell, D-Wash., and Rep. Adam Smith, D-Wash., would allow border agents to search electronic devices only if they had reasonable suspicions of wrongdoing. In addition, the legislation would limit the length of time that a device could be out of its owner's possession to 24 hours, after which the search becomes a seizure, requiring probable cause."
Operating Systems

Netbook Return Rates Much Higher For Linux Than Windows 663

ivoras writes "An interview with MSI's director of US Sales, Andy Tung, contains this interesting snippet: "We have done a lot of studies on the return rates and haven't really talked about it much until now. Our internal research has shown that the return of netbooks is higher than regular notebooks, but the main cause of that is Linux. People would love to pay $299 or $399 but they don't know what they get until they open the box. They start playing around with Linux and start realizing that it's not what they are used to. They don't want to spend time to learn it so they bring it back to the store. The return rate is at least four times higher for Linux netbooks than Windows XP netbooks.'"
Games

Review: Spore 605

The hype leading up to Spore was excessive. But then, so is the scope of the game; following the growth of a species from the cellular level to galactic domination was an ambitious goal, to say the least. Bringing evolution into the realm of entertainment was something Will Wright hoped and gambled he could do after the success of the Sim franchise. But rather than evolution, Spore became more about creation — creation that allows a single-player game to include the community, as well. It ties the various parts of the game together to make Spore very entertaining as a whole. Read on for my thoughts.
Science

Are 68 Molecules Enough To Understand Diseases? 133

Roland Piquepaille writes "A researcher from the University of California at San Diego (UCSD) claims that 68 molecules can explain the origins of many serious diseases. After reviewing findings from multiple disciplines, he 'realized that only 68 molecular building blocks are used to construct these four fundamental components of cells: the nucleic acids (DNA and RNA), proteins, glycans and lipids,' and he said that 'these 68 building blocks provide the structural basis for the molecular choreography that constitutes the entire life of a cell.'"

Comment Vote with your Wallet (Score 1) 900

I know there's a lot of Spore love around (heck, I'm excited, too), but the only way to let companies know that this kind of stuff is going too far is by voting with your wallet-- if enough people don't buy the game, or buy it and return it to major retailers saying it's defective because they don't have a home internet connection, then something will change.

If your "shiny new game" lust overwhelms your outrage, then don't bitch about it here. You have a choice whether you play the game, and your money is how businesses judge their actions.

Math

Is Mathematics Discovered Or Invented? 798

An anonymous reader points out an article up at Science News on a question that, remarkably, is still being debated after a few thousand years: is mathematics discovered, or is it invented? Those who answer "discovered" are the intellectual descendants of Plato; their number includes Roger Penrose. The article notes that one difficulty with the Platonic view: if mathematical ideas exist in some way independent of humans or minds, then human minds engaged in doing mathematics must somehow be able to connect with this non-physical state. The European Mathematical Society recently devoted space to the debate. One of the papers, Let Platonism die, can be found on page 24 of this PDF. The author believes that Platonism "has more in common with mystical religions than with modern science."
The Courts

Should RIAA Investigators Have To Disclose Evidence? 216

NewYorkCountryLawyer writes "A technology battle is raging in UMG v. Lindor, a court case in Brooklyn. The issue at hand is whether the RIAA's investigator SafeNet (the company that acquired MediaSentry) now needs to disclose its digital files, validation methodology, testing procedures, failure rates, software manuals, protocols, packet logs, source code, and other materials, so that the validity of its methods can be evaluated by the defense. SafeNet and the RIAA say no, claiming that the information is 'proprietary and confidential'. Ms. Lindor says yes, if you're going to testify in federal court the other side has a right to test your evidence. A list of what is being sought (pdf) is available online. MediaSentry has produced 'none of the above'. 'Put up or shut up' says one commentator to SafeNet."
The Internet

Proposed Bill in Tennessee Penalizes Schools for Allowing Piracy 129

An anonymous reader brings us an Ars Technica report about a proposed bill in Tennessee which would require state-funded universities to enforce anti-piracy standards. The universities would be forced to "track down and stop infringing activity" or risk losing their funding. The U.S. Congress requested last year that certain universities do this voluntarily. Quoting: "Efforts taken by universities thus far to deter and prevent piracy have had mixed results. The University of Utah, for instance, claims that it has reduced MPAA and RIAA complaints by 90 percent and saved $1.2 million in bandwidth costs by instituting anti-piracy filtering mechanisms. However, the school revealed that their filtering system hasn't been able to stop encrypted P2P traffic and noted that students will find ways to circumvent any system. The end result, some say, will be a costly arms race as students perpetually work to circumvent anti-piracy systems put in place by universities."
It's funny.  Laugh.

Submission + - Data flows faster downhill (infoworld.com)

CaptainTact writes: "Found this on InfoWorld's page, under the Tales From the Trenches section:

"It was the peak of the dotcom boom and I worked for a travel agency that was buying out Mom-and-Pop travel shops from Seattle to Miami — mid-1999, if I remember correctly. I was part of the traveling network team that was responsible for acquisition network and server reviews and employee evaluations of said acquisitions.

I was sent off to our recently acquired sister site in Seattle, a mega travel company that had about 10 smaller sites and a supposedly superior sys admin — or so I was informed. Eric was the only IT guy for this company, and he had just gotten his CCNA AND MCSE. It was my job to review Eric and the site to determine whether he should stay or go and what other changes might be necessary.

Eric walked me through the impressive datacenter (or server room at the time), which was a pristine room reflective of a man who took pride in his work. Cables were run in cable trays, zip ties kept them bunched neatly, and each rack was arranged in the same fashion, hinting at consistency and forethought. The site was not typical of a Mom-and-Pop shop with Kmart network gear everywhere — this was a true IT operation. He took time to give me specifics on the networking setups, spanning tree-enabled or not, and their redundant setups (rare in that day). He also described each server and its function (file, mail, and so on). This guy seemed to know his stuff, and I like to think I'm not easily impressed.

After that impressive tour, we sat down in a conference room to discuss the future of the server room and the remote sites. Our first enterprise initiative was to move the sites onto MS Exchange, so I asked him which server was least utilized and running NT4 SP6 to which he proudly replied, "Oh, sorry, we only run the stable version of Windows 95 on our servers here. NT4 is the worst thing ever from Microsoft."

Wait. What? I sat in disbelief as I listened to Eric describe these servers, all the while his manager nodding her head in agreement. He failed to mention this to me in the walk-through, and I just couldn't believe this guy with the enviable server room had just said such a thing. I chuckled and said, "Funny guy. You had me going there." I proceeded to ask again which server was ready. Eric looked at me, contempt now plainer on his face, and told me matter-o-factly: "I would never joke about something so serious. Windows 95a, NOT THE B CRAP or 98," he said at a higher volume, "is the best OS for a server environment. Windows NT will soon go away and those idiots who installed it will run back to 95. You'll see."

"OK, we'll cover that topic at a later date," I said, thinking it best to move on. "We can build out a spare server and rack it with the company-required NT4 install and put it in the open section at the bottom of the last rack."

It was Eric's turn to laugh next as he told me, "Well that's fine, if you want the e-mail to be really slow."

Confused, I ask him to explain, expecting to hear that one of the switches was an older model 10MB Ethernet or 4MB token ring or something. Those weren't all that much slower, but some people didn't know that.

"See," he said in a voice rich with condescension, "data flows faster downhill. You should always put servers at the top of a rack with switches below. That way the data from the server is faster to the user."

Wow, did I miss that physics lesson when I was taking my networking class all those years ago? Did the instructor reveal this important tidbit while I was out on a bathroom break? This time I laughed hard. Really hard. "Eric," I said, "you are either pulling my leg or you genuinely believe that crock of bull." His manager then piped up to inform me that Eric's skills were not in question and my review of his knowledge would not determine whether he kept his job and would I please stop insulting him.

So for value-added entertainment and lack of anything else constructive to do under the circumstances, I called my boss and team lead for a conference call. I started out happily, telling them about the server room and its layout, seamless design, and work of art, blah blah. I watched as Cathy, Eric's manager, smiled that I-told-you-off-and-you-had-to-listen smile. Then I hit on the Windows 95A servers and location of said servers with data-flow technical details. There was silence on the line. My boss was furious that I'd bothered him with such idiocy, and nobody seemed to think it was funny.

"If you know better, then you run it!" threatened Eric. Challenge accepted: My boss told him to pack up his things. During the next few months, we unearthed thousands of problems (virus, file corruption, and so on) and a nice stash of porn on those Windows 95 servers as we converted them. Seems Eric's pretty server room was much more impressive than his grasp of gravity.""

Networking

Submission + - Flexible optic fiber for "last mile" conne

bn0p writes: According to an article on Ars Technica, a Korean company has developed a low-cost, flexible, plastic optical fiber that could help solve the "last mile" problem and bring 2.5 Gbps (bits per second) connections to homes and apartments. While not as fast as glass fiber, it is significantly faster than the copper connections in use today.

In related news, Corning recently announced a flexible glass fiber that can be bent repeatedly without losing signal strength. The Corning fiber incorporates nanostructures in the cladding of the fiber that act as "light guardrails" that keep the light in the fiber. The glass fiber could be as much as four times faster than plastic fiber.

Neither fiber is available commercially yet, but both should help improve data rates to the home when they are deployed.

Slashdot Top Deals

Anyone can make an omelet with eggs. The trick is to make one with none.

Working...