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Comment Re:Do you hear me now?? (Score 1) 510

Don't pay the termination fee! Tell them you lost your job and your destitute. What are they going to do, pursue to the ends of the Earth and the end of your life? Big deal, they'll send threatening letters from collection agencies, and they'll ding your credit rating. So what! Your credit rating isn't worth as much these days in a bad economy. And over time you can rebuild it.

I was laid-off from the largest pharmaceutical company in the world in a round of massive lay-offs, lost my home to a short sale (yes, you, the American tax payer are paying for my mortgage), and after speaking with Certified Financial Advisors and Mortgage Crisis Counselors, Banks, companies, etc... have very little recourse to pursue you unless you owe many 10 of thousands or millions of dollars. If you don't have the money, you don't have the money. If you don't want to pay the termination fee, then don't pay it. Verizon will not spend the money to hunt you down, drag you into court, or have a State Marshall serve you with papers to report to court.

Comment Metabolism must be controlled (Score 1) 978

The key to losing weight is the control of metabolism. Acetyl-Coenzyme A Carboxylase (ACC) converts acetyl-CoA to malonyl-CoA, where malonyl-CoA is the first committed step in fatty acid biosynthesis. Malonyl-CoA inhibits mitochondrial fatty acid oxidation through feedback inhibition of mitochondrial carnitine palmitoyltransferase (CPT1), and therefore plays key roles both in controlling the switch between carbohydrate and fatty acid utilization in liver and skeletal muscle and also in regulating insulin sensitivity in the liver, skeletal muscle and fat. Inhibition of acetyl-coenzyme A carboxylase not only switches metabolism from lipogenesis to whole-body fatty acid oxidation, it also prevents the synthesis of triglycerides which contribute to atherosclerosis, a leading cause of cardiovascular disease.

Useful links:
http://en.wikipedia.org/wiki/Acetyl-CoA_carboxylase#cite_note-pmid9449982-1

http://en.wikipedia.org/wiki/Malonyl-CoA

Comment Re:More hair-brained ideas for "Global Warming" (Score 2, Interesting) 418

Sorry I wasn't more specific, hemoglobin will not transport CO2 by binding to the iron in the heme macrocycle (http://en.wikipedia.org/wiki/Heme) (http://en.wikipedia.org/wiki/Macrocycle). I did my graduate work in metallated porphyrin chemistry (http://en.wikipedia.org/wiki/Porphyrin). And thank you for pointing out the Bohr effect. I didn't expect the discussion to get 'this' technical, but it was nice to see the interest.

Comment Re:More hair-brained ideas for "Global Warming" (Score 5, Interesting) 418

As an experienced scientist, placing any form or CO2 in water is a very bad idea. Eventually it will change states from solid to gas or from solid to dissolved in water, which then is known as carbonic acid. This is exactly how your body deals with CO2, it is dissolved in your salty blood, where it is expelled as a gas from the lungs. Only hemoglobin transports oxygen to the tissues, it does not transport CO2 in any way shape or form. CO2 will influence the affinity oxygen has for hemoglobin, and in the presence of higher concentrations of carbonic acid, hemoglobin more readily releases oxygen to the surrounding tissues. Hemoglobin will also transport CO, carbon monoxide, but the binding is through carbon-metal (iron) back bonding, not through the oxygen. I didn't even mention the unknown effects this would have on marine life.

The only way to curb CO2 in the atmosphere is to stop burning fuel and let natural vegetation grow. This also means letting forests GROW and not clear cutting for land development, wood, and paper.

Comment Potentially a great idea, but... (Score 1) 252

Potentially a great idea, but what happens when the opposition/enemy figures out how to block/jam the First-Person-View Fly-By-Wire carrier waves used to control these planes? YouTube has some excellent videos on First-Person-View model airplane flying with conventional technology for the home hobbyist. Just type in 'FPV RC plane' to get a list of videos. I suppose if the enemy/opposition were to block the carrier waves, they would be lobbing bombs at themselves in a very uncontrolled manner.

Comment Re:Ethanol is just stupid (Score 4, Insightful) 894

I remember reading quite some time ago that some cars, specifically with turbochargers, and the right computer programming can reap some benefit of using alcohol. Saab, where most if not all of their cars are turbo charged, in the last few years has a smart computer that can tell what type of fuel being burned and adjusts the boost accordingly. Don't know if the extra boost required to reap the benefits of EtOH causes more wear and tear, but I would suspect so. Diesel and bio-diesel are better alternatives to gasoline, especially since diesel is made differently now. The Volkswagon Jetta with a 4-cylinder turbo diesel (2.0L) can accelerate as fast as a V6 and it doesn't produce all of the black exhaust that diesels of yesteryear did. Diesel engines are more expensive to build because of the high heat and torque they produce.

I think the American auto industry needs to wake up and start engineering its vehicles for the highest mileage possible by using diesel and hybrid and stop reducing the amount of plastic and sound insulation in cars. It's easy to reduce weight by cutting plastic and sound insulation, which leads to interiors falling apart prematurely and driving the public to foreign vehicles.

I own a 1999 Saab 93 and really like the car - low maintenance, but service is expensive. Also, it's not rusting anywhere. Recently Yahoo recommended Saab and Volvo as excellent cars to own long-term because, well, they last a long time and are built well. YouTube has a few videos of some suped-up Saabs in drag races. One, is a recent All-Wheel Drive 2000-year body style that fries all 4 tires most spectacularly - and it's done with a 4-cylinder turbocharged engine.

Comment As a pharmaceutical scientist.... (Score 1) 420

I don't eat much "processed" foods. No colas, sodas, candy bars, cheezy puffs, etc... What I do eat are home cooked natural foods with locally grown herbs and spicies. Hell I make my own bread - no high fructose corn syrup in there. The important lesson here kids is start making food you can't find at the local grocer.

I almost for got to mention - I look 15 years younger than most people my age.

Comment AdBlocker exists for a reason... (Score 1) 615

AdBlocker Plus exists for the purpose of helping people navigate the web without being inundated with obtrusive flash-based pointless graphics bandwidth-hogging advertisements that don't pertain to my interests. I understand that companies need to make money, but somehow Google and its text-based ads manage to be unobtrusive and are more likely to pertain to my interests. I've clicked on more Google text-based ads than flash-based ads. To me, all these flash-based ads on CNN and other websites are like going to New York City and trying to find the addresses of businesses you're trying to seek, which is one reason why having a Garmin GPS unit is very helpful for those in unfamiliar places.

My message to the advertising world: Change your ways and get away from the 'ALL IN YOUR FACE' advertising on the web, because if you don't, you'll go the way of the dinosaur. Understand that at this time more than any other, people's time is worth more than in the past. If you're going to advertise, do so unobtrusively and intelligently, like Google, or even besting Google. Trying to find the information we need while being bombarded with flashy graphics is very distracting, which is why I'm a strong advocate of AdBlock Plus. I hope the author of AdBlocker Plus does not change the FireFox Plugin, forcing the advertising industry to change the way it advertises. A simple Bolded text headline will do, with an unbolded paragraph below explaining in more detail the service/product being offered.

Nothing pisses me off more than my time being wasted and attention distracted. The advertising world needs to respect people, and if it doesn't, then more really useful plugins like AdBlocker Plus will become mainstream. Here's another note to web administrators and advertisers: If I can't circumvent the obtrusive flash-based advertisements, I stop going to that website. Seriously, the industry needs to change.

Also, Kudos to NoScript!

OK, end of my rant/tirade.

Comment NO ELECTRICITY! (Score 1) 1117

Back in my dad, the only laptops students had was a small rectanglar slab of thin slate with a wooden periphery and the input method used a small piece of chalk. Cheap and effective! No viruses as in modern computers, unless of course you coughed or spit on it, then shared it with your classmates. Ah.... Those were days.

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