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Science

Submission + - Supercomputer sets protein-folding record (nature.com)

Nicros writes: A specially designed supercomputer named Anton has simulated changes in a protein's three-dimensional structure over a period of a millisecond — a time-scale more than a hundred-fold greater than the previous record. Proteins are strings of amino acids that fold into intricate structures, which largely determine a protein's function. Understanding how and why proteins take on specific shapes has long been a goal of structural biologists, but previous computer simulations were too short to fully model the process.

Submission + - How to find Wifi interference? 4

Nicros writes: So I am experiencing a somewhat bizarre thing. Almost every evening, between 8:30 and 10- my wifi seems to just die. This, in itself, could be explained by a crappy wifi source or some hardware failure, except that I know both of my neighbors are experiencing the SAME loss of signal at the same time! While the wifi is down, the lan is just fine, and any plugged into cat5 can access the internet just fine. It is only the wifi portion of our routers that we cant access.

So a couple things come to mind- is it possible that some other neighbor arrives at home and is the type that turns on their router from 8:30-10? And that there is something that is hosing our wifi? Or what other possible causes may there be?

I have tried looking around for software to help identify the source of interference, but either they are ridiculously expensive for a home user or my card (intel link 1000 BGN) isnt supported (like by netstumbler).

Anyone have any suggestions on how I can track this down?

Thanks!

Comment How is this different from 'Spirit Mode'? (Score 1) 303

I don't really get it. How is this any different than entering 'Spirit mode' or whatever from any number of games? Prey is a good example. And bringing some object with you? You can call it whatever you want, 4th dimension, Spirit World, Dreamtime etc. but it still seems like the same concept to me.
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NHS Should Stop Funding Homeopathy, Says Parliamentary Committee 507

An anonymous reader writes "Homeopathic remedies work no better than placebos, and so should no longer be paid for by the UK National Health Service, a committee of British members of parliament has concluded. In preparing its report, the committee, which scrutinizes the evidence behind government policies, took evidence from scientists and homeopaths, and reviewed numerous reports and scientific investigations into homeopathy. It found no evidence that such treatments work beyond providing a placebo effect." Updated 201025 19:40 GMT by timothy: This recommendation has some people up in arms.

Comment Re:Yes and No (Score 1) 599

I find learning a new language is easy, learning the new tools is a pain in the ass. Java was easy. I found Eclipse RCP/Spring/Hibernate more difficult to learn. C# was easy too. Learning WPF, WCF and all the .NET 3.5 (and now 4.0) technologies was much harder (still doing it in fact). Not to say these things are truly difficult, they're not. But there is a LOT to them and it takes time to understand it all. I don't think most programming jobs are about the language at all anymore, its more about the tools used to build apps. Understanding the syntax of a language seems to be kind of a given.

Comment Re:So it's a fnacy nmae (Score 1) 1345

I'll second this one, and take it even a step further. I worked in academia for a while, surrounded by our (and other) nation's brightest scientists. As a general rule, they were indeed brilliant. But there was also a large group of people with MD's or PhD's who were just friggin IDIOTS. I mean no common sense whatsoever, no ability to function in a normal way. But they got good grades in school, didn't they! Maybe even went to a school for the gifted because they were so 'smart'?

Which brings me to the second point- I bet if you were to track the success (don't ask me how to define success, use your own definition) of average people vs the 'smart' ones you might be suprised. I doubt very much it would be skewed towards the smart ones. My personal theory is the smart ones know what they are in for so don't try and take risks they feel are unacceptable. The less smart just go for it, and sometimes succeed in a spectacular fashion.

Software

Submission + - How to move into management?

Nicros writes: I have spent the last 10 years or so as a senior software engineer, and see a looming dilemma heading my way. I just turned 40, and while I really enjoy the technical aspects of my work, I also enjoy leading teams and projects- which suggests I might enjoy a career path in more of a leadership role- maybe management to start, director after some experience, etc. I also don't see myself as a software engineer banging away in my cube when Im 45 or 50.

But I'm having a hard time trying to map the transition from a technical role to a leadership position. I have had direct reports, and have led several successful projects, so have some experience but was never officially a manager. Most of the positions I see for lead roles or management require many years of experience, which I dont have. Trying to move into this position where I currently work doesnt seem to be an option, as there are just no resources to hire more people, and no incentive for them to move me into a different role.

So what would be a strategy to move forward along this career path from my current position? Just bang away at management positions? Software Lead positions? Software Project management?

I would love to hear suggestions or experiences from people who are in leadership positions after making a similar transition.
Programming

Submission + - New job, new software, new problem?

Nicros writes: So I just got a good paying job as a senior software engineer at a biotech company. When I was hired, I was told that I would be leading a project, coding and re-architecting a legacy application which they wanted to 'productize'. Sounded cool! So then I started, and discovered that although all of those things are factually correct, the reality is a bit different.

The code base is over 180,000 lines of really complex unmaintainable code. Several files (this is C# btw) have over 25,000 lines per file (!). And that is for 1 class with 125 methods- so you can do the math how big each method is. Additionally, this is scientific software, so it is very, very complex.

I'm having a hard time even running metrics on these things because they are such memory hogs for the tools available.

So okay, thats a lot of work to refactor and rearchitect that, maybe even for a team. Oh yeah, I have probably less than a year.

I came from a position where I was a project lead, technical lead and a manager. This new position would seem to be me, coding, alone, for a very long time. Not learning that much, and Im not seeing much career enhancement other than becoming a crack C# programmer (which would be one good thing anyway). So I guess Im still a lead. But overall, I feel I have taken a step back career wise. The company is also, of course, resource limited so I may or may not be able to hire some help.

So, I would be very interested in hearing what others thing about this situation, and possible ways to deal with it in a positive manner. Are there career risks here? I do need the job, so I cant just bail. I also would not like to let them down, they hired me to do a job and I accepted- I want to do it well. So I really would like to make the best of this and help my career at the same time, but Im having a hard time seeing any path that leads to success.

Thoughts? Suggestions?

Comment I doubt it! (Score 1) 221

I hate misleading articles like this.

Have to say Im pretty sure this guy would have been able to walk as described sans spider bite. In fact, if he had been hospitalized several years before maybe the outcome would have been the same.

And on top of that, I doubt even more that he was bitten by a brown recluse. These are extremely rare if not nonexistant in California (http://spiders.ucr.edu/myth.html).

And on top of THAT, what looks like a brown recluse spider bite is most often a misdiagnosed staph or other necrotic infection (http://spiders.ucr.edu/necrotic.html).

And despite all this misinformation, probably safe to say people will believe that brown recluse spider bites are like the next stem cell technology.

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