Comment Re:Not Evolution (Score 3, Informative) 115
But how does Evolution prune the repication mechanism itself? If an early replicator was very sloppy and mutation prone, then any possible advantages occuring by random mutation would have little chance to be tested before other random mutations overwrote them or other mutations killed off the organisms carrying that mutation. Working backwards, let's start with modern DNA, in cases where there are many additional mechanisms to cut the mutation rate so the non-random part of Evolution has more time to work. Putting DNA inside a walled cell, and making that cell nucleated, both reduce the exposure of the DNA to chemicals that can mutate copies. Multicellularity further shields the DNA from some more mutagens, and lets Evolution prune cells with bad copies by apoptosis, which can't be used by single celled organisms. Right there, we have a trend in Evolution - Nature seems to be trying to reduce error rates to target, as you put it, the Goldilocks range. "Advanced" organisms, such as us, or mosquitos or oak trees, have many features that make the selection rate occur at an optimum, where Nature gets enough time for selection processes to occur. In fact, sexual selection is probably just another form of targeting that Goldilocks range, and I'm sure a professional biologist can think of may more examples than the four I've mentioned. Some more minor steps in this pattern might include the evolution of Alcohol Dehydrogenase enzymes and others, but that's getting beyond my depth.
But if we extrapolate a historical trend from that, the mutation rate must have been higher for 'primative' DNA based life, but the selection pressure must have been lower. Mutation must have been still higher if RNA was once the core molecule of heredity, which seems pretty solidly established. And if there's several more primative replicators, selection pressure must have moved glacially compared to the modern era. So how did selection have time even in 3 billion years to evolve DNA itself? If the earliest replicators were something like crystaline clays that were subject to a very modest amount of selection by erosion, as some biologists have speculated, how do we get the time for these to evolve through many stages to RNA and then DNA and eventually all the extra trimmings of today? Given that we've been in a DNA based biosphere for close to 1.5 billion years, that's about half the time since Earth cooled enough to support organic compounds,, and we're trying to cram probably at least 5 or 6 earlier replicators into less than half the time, knowing that each one was subject to less selection pressure than it's successor probably by orders of magnetude.