Comment Re:Democracy? (Score 1) 371
"Some of the uses for which PGS is intended are particularly concerning, such as assessments for BRCA-related genetic risk and drug responses (e.g., warfarin sensitivity, clopidogrel response, and 5-fluorouracil toxicity) because of the potential health consequences that could result from false positive or false negative assessments for high-risk indications such as these."
Show that the level of false positives/negatives is higher with genetic testing than with conventional testing, and you might have a point. Otherwise, alarmist "OMG MY BREASTS!" scare mongering.
For instance, if the BRCA-related risk assessment for breast or ovarian cancer reports a false positive, it could lead a patient to undergo prophylactic surgery, chemoprevention, intensive screening, or other morbidity-inducing actions, while a false negative could result in a failure to recognize an actual risk that may exist."
Correct, but -- again -- irrelevant unless the error rate is higher than in hands-on testing that's currently being used.
"The risk of serious injury or death is known to be high when patients are either non-compliant or not properly dosed; combined with the risk that a direct-to-consumer test result may be used by a patient to self-manage..."
Ahh...THERE it is. We can't have patients going around getting informed about what's in their own bodies and making decisions based on that information. That's the purview of PROFESSIONALS.
Kind of like auto mechanics telling you they're the only ones that should be allowed to read the OBD messages from your car.