Comment DDR vs. Estrogen... FIGHT! (Score 1) 1091
In my experience, hormones have a lot more to do with athletics than do chromosomes.
I'm a transsexual woman who was born male (with XY chromosomes and all that usually entails). I competed in statewide Dance Dance Revolution tournaments and did well. Then, around age 24 when I started transitioning to female and taking estrogen and androgen blockers, my stamina decreased drastically, my muscle mass decreased and my body fat ratio increased. I was once able to play for 7.5 hours straight, and soon after transitioning I could only play for a couple of hours without getting exhausted. 10-footer songs that I used to be able to pass without much trouble, I couldn't make it all the way through anymore. I've been training to build up my stamina, and I'm getting stronger and more fit, but I'm still not at the level I was back when my hormonal balance was completely different.
It's not surprising that hormones are the most influential factor, because what are steroids, after all? Testosterone.