Comment Question for sequencing expert. (Score 4, Interesting) 128
How accurate is it for the media to say a "complete" genome was sequenced? I know a little molecular biology and have been lead to believe that certain types of DNA, (centromeres, telomeres, other such regions with lots of repetitive sequences or "fragile sites") are very hard to sequence reliably. Are these "swept under the rug" in a "complete" sequence? Perhaps a related question, how are non-coding regulatory portions of chromosomes handled in whole genome analysis?