I've never used AdBlock — I just use NoScript. I'm not blocking based on content, I'm just enforcing tighter security on my computer.
It cleanly kneecaps admonger arguments — static ads (I also disable animated gifs) and text ads display just fine, but you don't have my permission to run Flash, Java, or JavaScript on my system. And strangely enough, NoScript's control is finely-grained enough to give a site general permission to execute content without also granting access to skeevyads.cx and other bastions of consumer rights.
(And I'd use NoScript even if it did none of those things, because the act of *not loading a PDF by default* has saved me hours and hours of dodging lockups and crashes.)