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Comment Good Omens (Score 1) 499

The obesity problem is best understood not as the result of the overconsumption of a single macronutrient, but from a skewing of the proportion of each macronutrient in our diet - notably the dwindling quantity of protein in processed food products. The paucity of protein relative to fats and carbohydrates in processed foods drives the overconsumption of total energy as our bodies seek to maintain a target level of protein intake.

Reminds me of' Sable / Famine's pre-apocalyptic fast food business in 'Good Omens':

"Two years of Newtrition investment and research had produced CHOW(TM). CHOW(TM) contained spun, plaited, and woven protein molecules, capped and coded, carefully designed to be ignored by even the most ravenous digestive tract enzymes; no-cal sweeteners; mineral oils replacing vegetable oils; fibrous materials, colorings, and flavorings. The end result was a foodstuff almost indistinguishable from any other except for two things. Firstly, the price, which was slightly higher, and secondly, the nutritional content, which was roughly equivalent to that of a Sony Walkman...MEALS(TM) was Sable's latest brainwave. MEALS(TM) was CHOW(TM) with added sugar and fat. The theory was that if you ate enough MEALS(TM) you would a) get very fat, and b) die of malnutrition. The paradox delighted Sable."

Comment Re:*Yawn* I'll Wait for the Mint Edition (Score 1) 179

In light of some of the changes that have caused some huge controversies (having the window buttons on the right vs left is straight out of Gulliver's), maybe you mean "ignoring the very vocal minority who reject innovation, either from a need to feel elite or fear of change".

Moving the window buttons to the left is 'innovation'?

Comment Re:Surely ironic (Score 2) 276

"It's just complete nonsense, anyone working with smartphones at the time was completely unfazed by the iPhone - the first edition wasn't entirely dissimilar (and was notable underfeatured compared to) offerings from companies like Nokia, and HP with their iPaq phones.

Though 'nobody expected anything remotely like the epoch shifting device' is over the top, the main point is hardly complete nonsense. Most of the speculation was indeed heavily influenced by the iPod and older style smartphones:

http://www.businessinsider.com...

Apple was seriously considering a clickwheel-based design 15 months before the iPhone was unveiled:

http://www.idownloadblog.com/2...

Comment Re:So Obama canceled stem cell research? (Score 3, Informative) 86

"James Anderson, director of the NIHâ(TM)s Division of Program Coordination, Planning, and Strategic Initiatives, which administered the CRM, counters that only one application - that made by Kapil Bharti of the National Eye Institute in Bethesda and his colleagues - received a high enough score from an external review board to justify continued funding."

You can take this at face value, or assume academic politics, but it doesn't seem like party politics.

Comment Re:Lancaster (Score 1) 179

You're only as good as your last RAE :-)

http://physicsworld.com/cws/ar...

"An unofficial Physics World ranking that lists departments according to their average research score shows Lancaster on top and Cambridge close behind. Both departments also received the maximum 5* rating in the last RAE in 2001, but the other 5* departments - Oxford, Southampton and Imperial College London - fell outside the top 10 this time round. "

Comment Re:Op Out Knowledge? (Score 5, Insightful) 157

People (and genetic risks) are different. One person's 'making the most of my time left' is another's 'spending decades with the constant threat of a terrible disease blighting my life'. In Jim Watson's case, he was already at an age where presumably he'd made adequate provision for his loved ones (the link is with late, rather than early onset dementia). Knowing that he might be at increased (but very far from absolute) risk of losing his mental faculties late in life wasn't useful information to him, but might have led him to worry about something he could do nothing about. It's not hard to think of other scenarios where an individual may make the (perfectly valid) choice to not know everything about his genome.

Comment Re:Op Out Knowledge? (Score 1) 157

I doubt anyone is going to force you to know your faulty DNA, but opting out of knowing if given the choice is just stupid, and potentially very expensive - because you will change your mind on having that treatment once the symptoms appear, which might very well be too late.

What if there is no effective treatment? James Watson, co-discoverer of the DNA structure and one of the first people to have his entire genome sequenced, chose not to know the sequence of his APOE gene, some variants of which have been linked to an increased risk of late onset Alzheimer's disease.

Comment Re:Other similar situations (Score 2) 157

wasn't there a discovery that determined if you were likely to commit a crime? Or be serial killer or something like that?

How did that work out / what ever happened with it?

90% of murderers, and 99% of convicted rapists, have a copy of the SRY gene, which is much higher than its frequency in the general population (about 50%). SRY has been linked with aggressive behaviour, autism, and a preference for large, fast cars.

Comment Re:Is this how we're funding science now? (Score 1) 275

This "academic bioinformatics institute" is an LCC, not an actual academic institution :) Its a scam.

They claim to be a "non-for-profit research and development organization". They have a respectable list of publications, all the way up to co-authorship in a Nature paper, so doesn't look like a scam!:

http://bioinfo.pl/papers.html

Comment Re:Disproved? (Score 4, Informative) 20

No, the results are not disproven and certainly not shown to be fabricated, though you could be forgiven for thinking otherwise after the feeding frenzy about this paper on the internet. There are certainly grounds for scepticism, though. We'll have to wait until this has been thoroughly tested using the more detailed protocols that have now been made available before we can call it one way or the other.

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