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Comment Re:Yea, best form a comitee to consider all option (Score 1) 193

So how would you do an RCT for something like Ebola, a disease that really only manifests itself when it starts to spread? Would you ask for volunteers to be infected outside of an outbreak in ordered to test efficacy/safety? Is there an IRB board in the country that would authorize something like this?

I actually do agree that you don't want to get all Mavericky with drug experimentation. At a certain point though you need patients with the disease to test efficacy and safety. If the only time you have patients is during an outbreak then when else can you test in vivo responses?

Comment Re:the cure for AIDS (Score 1) 134

You could be a carrier for months to years and be a vector without showing up positive in a test.

Just for the record, this is not correct. While it is true that there is an eclipse period during which testing is not useful (as indeed, there is an eclipse period for any viral infection), for HIV that window is currently very small.

See:

  • Centers for Disease Control and Prevention. Monitoring selected national HIV prevention and care objectives by using HIV surveillance dataâ"United States and 6 dependent areasâ"2011. HIV Surveillance Supplemental Report 2013;18(No. 5). http://www.cdc.gov/hiv/library/reports/ surveillance/. Published October 2013.
  • Centers for Disease Control and Prevention and Association of Public Health Laboratories. Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations. Available at http://stacks.cdc.gov/view/cdc/23447. Published June 27, 2014..

Comment Re:why internet connected? (Score 2) 111

In fact, too much data has been shown to lead to more misdiagnoses in ER's.

Citation needed

What type of data are you talking about? Lots of largely irrelevant lab data? (oh look...an elevated ESR!) Or is it historical data (Why yes Doctor, I do have a metal plate in my head. Is that bad for an MRI?)

The clinical history is one of the most powerful diagnostic tools available. Even in the ED.

Comment Re:Linux Mint 17 (Score 1) 322

I finally decided to give linux (Ubuntu 14.04) a go as a primary OS on my new laptop with a win 7 vbox guest os. The install process is still a little rough around the edges (it took me a day to figure out that linux STILL doesn't support the raid chipset (intel) on my MB. Grrrr...).

But other than that, it is nice to have a real development environment and I was pleasantly suprised with how smoothly things integrate. VirtualBox is easy to work with and I had a guest OS installed with little hassle for my windows-specific software that I require. It's not a bad way to go.

Comment Re:JWs' view and my view (Score 1) 172

Plasma is primarily water with a collection of proteins (performing a variety of opposing functions) and should contain no viable cells. There is probably a chance of contamination with viable cells (probably more common in plasma derived from whole blood, but I have no data/sources to back this up) but this may also depend on the type of plasma (e.g. frozen vs liquid -- but again I have no data at the moment to indicate risks on one versus the other).

Comment Re:JWs' view and my view (Score 1) 172

I hate to break it to you, but platelets have mitochondria, consume energy, have cellular processes, activation/deactivation signals, etc..., so not quite sure that classifying them as "not living cells" is accurate.

On another note, you found contradictions in a Christian religion's doctrines? Shocking! Excuse me while I head to my fainting couch...

Comment Re:Most physicians have personally owned systems (Score 1) 143

Irrelevant. I.T failed in preventing him from doing it,

Agreed. I have never worked in a place (hospital or otherwise) where an end user could expose an internal service to the public.

HR failed

That pretty much sums up HR in general.

Drs. can afford their own private internet connection,

out of curiosity, how do you think this would work? A doctor is at the hospital, needs network access and.....has the phone company install a phone line in each of the wards she is rounding in? The "learning shit" is kinda important...like looking up the proper drug dose for a particular patient population, new diagnostic criteria, etc...

many docs think they are experts at computers. A minority actually are. Thus looks like a guy playing sysadmin who get left holding the dookie from incompetent net admins

Comment Re:It's about power, not being a customer (Score 1) 417

But look at the morning after pill. There was a monied interest behind that abortion related aspect so whoosh it was approved in 2 seconds.

notsureiftrolling.jpg but the morning after pill (e.g. Plan B) is a contraceptive, not an abortificant. Contrast with RU-486 (a genuine abortificant), which did get hung up quite a bit with approval, despite Big Pharma behind it.

Comment Re:Scientific Vamperisim! (Score 1) 178

You can store blood, properly prepared for up to 10 years at -65C. You have to use glycerol as a storage medium. People with rare phenotypes can freeze their own blood for use later when they need it. Athletes can freeze their blood to use it for doping at the appropriate time (see Tyler Hamilton's book The Secret Race for more of this type of usage).

Fresh blood can be stored from anywhere 35-42 days, depending on the storage solution used (e.g. CPDA-1 or CPD + additives).

...the more you know

Comment Re:And this is somehow supposed to be a surprise? (Score 1) 1010

I'm with the sib post here. I really enjoyed o-chem. It actually made me sad that I didn't take P-chem when I had the chance.

One thing that made the difference was that I prepared before the class even started -- I looked at the list of suggested readings in the course syllabus and went through one of the suggested resources ("Pushing Electrons"). An awesome little work book that made everything I learned in class very understandable.

And yeah - I took Ochem as a pre-req for med school and guess what? I still use information I learned in that pre-req as an MD. So much for the "you'll never use it!" argument!

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