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Comment Good news, needs more science (Score 5, Informative) 64

I know that I'm missing the human-interest angle of the story here, but as someone who works at a company that has performed some large-scale DNA vaccine production research (Vandalia Research, but please don't google us because the website is an embarrassment), I'm a little disappointed that the article didn't try harder to explain the difference between these new vaccines and the old egg-grown ones. I think a little science education is a good thing to provide, to pull back the curtain on the good that genetic engineering can do. The first-pass explanation was "Flublok uses insect proteins instead of eggs. (The other is Flucelvax, which relies on animal proteins.)" which is rather poor since the proteins don't replace the eggs, the insect/animal culture cells those proteins are grown in do. I don't expect an in-depth discussion of promoters or vectors, but more about the recombinant engineering involved than "insect cells are used to cultivate hemagglutinin" would be nice. For anyone interested in a more academic explanation of Flublok's approach, along with several other possible vaccine design strategies that will hopefully be coming soon, a good page to read would be http://www.ncbi.nlm.nih.gov/pm...

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