(Disclaimer: I don't expect to see significant breakthroughs any time soon in the quest to identify a discrete "simple" mechanism at Planck scale or similar, but that hasn't stopped Wolfram and unconnected others treating the possibility seriously. The extremely limited experimental simulations possible on foreseeable computers don't show signs of ruling out the possibility, so the thoughts below are confined to such a model and treat field theories et al as emergent.)
If there is a hypothetical microstructure in the form of a simple graph (as formally defined) or similar which is continually involved in determining the next local state based on the current local state via some "simple" (enough) mechanism/rule/Wolfram "program", then it should be obvious to many of us with deep experience in computing that there is a major unaddressed clock synchronisation problem that must be solved in order to produce the observed consistency of time across regions which cannot share a time signal.
I've recently speculated that the CMB might have a role in this given that, under certain measurement assumptions, space is approximately filled with CMB photons, with their omnidirectional passage being sufficient to stimulate a natural resonance in the microstructure. Obviously the neutrino flux, or the combination of both, could be part of such a story. And that might make local variation in radioactive decay rates correlated with neutrino flux variations no more surprising than the variation in refractive index between various forms of (transparent) condensed matter.
At this stage it is all speculation, and fun, but certainly not anti-scientific.