Hi Bruce!

Obviously I'm biased, since I work on the project -- but have you seen Public Knowledge Project's "Open Journal Systems"? It's FOSS and its goal is to automate the management and workflow for publishing an academic-style journal. It wouldn't do your layout etc. for you, but it would help with submission management, peer review, and a lot of the associated stuff that needs doing. See http://pkp.sfu.ca/ojs for the details.

Cheers,
Alec Smecher
Public Knowledge Project Team

Great, finally there's a way to get these damn lobsters off my crops!