The new world? It took the largest and most powerful empires of the times, several centuries, royal decrees, and hundreds of ships to get a handful of explorers to have establish colonies in the new world. When they got there, they found local indigenous populations that helped their efforts.
The same thing could be true for space. The local indigenous populations that help our efforts aren't necessarily beings, but could be as simple along the lines of nitrogen-fixing bacteria helping us on earth, or plants or other things we can eat, or help us with water, air, energy, etc...
Or space could be like Antarctica You never know until you get there.
I'm guessing space is going to be more like Antarctica, which doesn't mean you don't go there, it just means you don't colonize it right away, you just research it and see where it leads you...
Between global warming, tectonic plate movement, improved technology, open land exhaustion, and maybe even some ecological disaster (due to war or perhaps an asteroid collision), maybe we will actually colonize Antarctica someday, which seems like a reason to spend some time to better understand it today...