Submission + - Generating a Rat Pancreas in a Body of a Mouse (jst.go.jp)
kazekiri writes: According to the Japan Science and Technology Agency (JST), in a project with Tokyo University, they have succeeded in generating a rat iPSC (induced pluripotent stem cell)-derived pancreas in a body of a mouse(paper). The research team injected rat iPSC into mouse's fertilized egg with gene manipulation hindering the generation of pancreas, and implanted it in a uterus of a mouse, the foster mother. It has been confirmed that the pancreas of a born mouse is entirely made of rat iPSC, and the pancreas functions normally. This is a step towards achieving a goal of regenerative medicine to make human organs in bodies of other animals.